Evidence map›Paper›PMID 21789543›Full record

ReviewCurrent oncology reports2011

Primary mediastinal DLBCL: evolving biologic understanding and therapeutic strategies.

Pier Luigi Zinzani, Pier Paolo Piccaluga

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. [A case report of anterior-mediastinal bulky lesion].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2012
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pier Luigi ZinzaniInstitute of Hematology and Medical Oncology "Seràgnoli", University of Bologna, Italy. pierluigi.zinzani@unibo.it
Pier Paolo Piccaluga
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary mediastinal diffuse large B-cell lymphoma is a quite rare clinicopathologic entity. Molecular analysis shows it to be distinct from other types of diffuse large B-cell lymphoma, and some retrospective analyses suggests that it may respond better to third-generation chemotherapy regimens than to the more commonly used CHOP. The addition of rituximab could reduce these differences; the role of consolidation with local radiotherapy, which is often used to treat residual mediastinal masses, remains. The real role of FDG-PET scanning requires prospective studies, and it is hoped that this may allow the de-escalation of radiation therapy accordingly to yield reliable prognostic information.

Indexed as

Antibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsHumansImmunophenotypingLymphoma, Large B-Cell, DiffuseMediastinal NeoplasmsPrognosisRituximabAntibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsRituximab

Identifiers

PMID21789543
OpenAlexW1979781733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.