Evidence map›Paper›PMID 21789370›Full record

ArticleClinics (Sao Paulo, Brazil)2011

Vitamin D status in patients with Behcet's Disease.

Saliha Karatay, Kadir Yildirim, Ali Karakuzu, Ahmet Kiziltunc, Ragip Ismail Engin, Yonca Bavli Eren, Akin Aktas

Open access · goldAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Vitamin D status in recurrent aphthous stomatitis.Postepy dermatologii i alergologii · 2017
    Article
  7. Article
  8. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Saliha KaratayDepartment of Physical Medicine and Rehabilitation, Ataturk University, Medical Faculty, Erzurum-Turkey. skaratay73@hotmail.com
Kadir Yildirim
Ali Karakuzu
Ahmet Kiziltunc
Ragip Ismail Engin
Yonca Bavli Eren
Akin Aktas
Atatürk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study investigated the serum 25-hydroxyvitamin D levels of patients with Behcet's Disease. DESIGN AND

methodsThirty-two patients with Behcet's Disease and 31 matched healthy controls were enrolled in this study. The erythrocyte sedimentation rate (ESR) and the levels of C-reactive protein (CRP), serum 25-hydroxyvitamin D, calcium (Ca), phosphate (P), and total alkaline phosphatase (ALP) were measured in both groups.

resultsThere were no significant differences between the two groups regarding demographic data. The serum 25-hydroxyvitamin D levels of patients and controls were 13.76 (range: 4.00-35.79) and 18.97 (range: 12.05-36.94) ng/ml, respectively. In patients with Behcet's Disease, 25-hydroxyvitamin D values were significantly lower than those of the healthy controls (p<0.001). Serum Ca, P, and ALP levels were similar in both groups. Serum ESR and CRP levels were significantly higher in patients than controls (p<0.05). There was no correlation between 25-hydroxyvitamin D levels and age, body mass index (BMI), disease duration, ESR, or CRP levels. Multivariate regression analysis parameters showed that smoking, alcohol intake, and use of colchicine were the main predictors of 25-hydroxyvitamin D levels. Of the parameters studied, the largest impact was due to colchicine therapy (p<0.001). We did not find a significant relationship between the use of corticosteroids and 25-hydroxyvitamin D levels.

conclusionOur results suggest that serum 25-hydroxyvitamin D levels are decreased in patients with Behcet's Disease. Smoking, alcohol intake, and use of colchicine appear to affect vitamin D levels.

Indexed as

AdolescentAdultAlkaline PhosphataseBehcet SyndromeBiomarkersBlood SedimentationCalciumCase-Control StudiesColchicineC-Reactive ProteinDisease ProgressionFemaleHumansMaleMiddle AgedPhosphates25-hydroxyvitamin DAlkaline PhosphataseBiomarkersCalciumColchicineC-Reactive ProteinPhosphatesVitamin D

Identifiers

PMID21789370
PMCPMC3109365
OpenAlexW2166300459

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.