Evidence map›Paper›PMID 21789068›Full record

ArticleTherapeutic advances in urology2009

Overactive bladder in males.

Roger R Dmochowski, Alex Gomelsky

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Therapeutic advances in urology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01457573 (Urinary Nerve Growth Factor as a Biomarker for Medical Treatment of Male Lower Urinary Tract Symptoms), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01457573 phase4completednot on this mapstarted 2011, after this paper: background citation

Urinary Nerve Growth Factor as a Biomarker for Medical Treatment of Male Lower Urinary Tract Symptoms: A Pilot Trial

TypeinterventionalSponsorTimothy Boone, MD, PhDRan2011 to 2014Enrolled10ConditionsLower Urinary Tract SymptomsArmsTamsulosin, Solifenacin
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Anesthetic options for Rezūm water vapor therapy Is minimal sedation tolerable for a minimally invasive procedure?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. PATTERN OF OVERACTIVE BLADDER IN SOUTHEAST NIGERIA.Journal of the West African College of Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Roger R DmochowskiProfessor, Department of Urologic Surgery, Vanderbilt University Medical Center, A-1392, Medical Center North, Nashville, TN 37232, USA.
Alex Gomelsky
Louisiana State University Health Sciences Center Shreveport · USVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of overactive bladder (OAB) symptoms is considerable in both men and women and the impact on quality of life (QOL) is equally substantial. Ironically, despite nearly equal prevalence, OAB symptoms in men are infrequently treated, and often with medical therapies aimed at bladder outlet obstruction (BOO). In this review, we examine the pathophysiology of OAB and its evaluation in the context of benign prostatic hypertrophy and concomitant BOO. We then consider the efficacy and safety of individual therapeutic options for lower urinary tract symptoms in men, focusing on the mainstays of medical therapy: α-adrenergic blockers, 5-α reductase inhibitors, and antimuscarinic agents. Finally, we aim to comment on new therapeutic strategies and targets that may one day be available for the treatment of male OAB.

Indexed as

anticholinergicbenign prostatic hypertrophyoveractive bladder

Identifiers

PMID21789068
PMCPMC3126063
OpenAlexW2073709013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.