ReviewMicrovascular research2011
Wide-field functional imaging of blood flow and hemoglobin oxygen saturation in the rodent dorsal window chamber.
Review in Microvascular research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 47 citations in OpenAlex.
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- Applications of Intravital Imaging in Cancer Immunotherapy.Bioengineering (Basel, Switzerland) · 2024Review
- Endocavity ultrasound and photoacoustic system for fetal and maternal imaging: design, implementation, andJournal of medical imaging (Bellingham, Wash.) · 2021Article
- Intravital Vascular Phototheranostics and Real-Time Circulation Dynamics of Micro- and Nanosized Erythrocyte-Derived Carriers.ACS applied materials & interfaces · 2020Article
- Microvascular Effects of Pulsed Dye Laser in Combination With Oxymetazoline.Lasers in surgery and medicine · 2020Article
- Handheld motion stabilized laser speckle imaging.Biomedical optics express · 2019Article
- Site-specific pharmaco-laser therapy: A novel treatment modality for refractory port wine stains.Journal of clinical and translational research · 2019Review
- Correcting for motion artifact in handheld laser speckle images.Journal of biomedical optics · 2018Article
- Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer.Scientific reports · 2017Article
- Article
- Hemoporfin-mediated photodynamic therapy on normal vasculature: implications for phototherapy of port-wine stain birthmarks.Journal of clinical and translational research · 2016Article
- Laser speckle imaging based on photothermally driven convection.Journal of biomedical optics · 2016Article
- Targeted narrowband intense pulsed light on cutaneous vasculature.Lasers in surgery and medicine · 2015Article
- Talaporfin sodium-mediated photodynamic therapy alone and in combination with pulsed dye laser on cutaneous vasculature.The Journal of investigative dermatology · 2015Article
- Implanted cell-dense prevascularized tissues develop functional vasculature that supports reoxygenation after thrombosis.Tissue engineering. Part A · 2014Article
- Photothermal laser speckle imaging.Optics letters · 2014Article
- Multi-modality imaging of a murine mammary window chamber for breast cancer research.BioTechniques · 2014Article
- Early Surgical Decompression Restores Neurovascular Blood Flow and Ischemic Parameters in an in Vivo Animal Model of Nerve Compression Injury.The Journal of bone and joint surgery. American volume · 2014Article
- In vivo spectral and fluorescence microscopy comparison of microvascular function after treatment with OXi4503, Sunitinib and their combination in Caki-2 tumors.Biomedical optics express · 2014Article
- Forecasting new development of tumor areas using spatial and temporal distribution profiles of hemoglobin saturation in a mouse model.Journal of medical imaging (Bellingham, Wash.) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
The rodent dorsal window chamber is a widely used in vivo model of the microvasculature. The model consists of a 1cm region of exposed microvasculature in the rodent dorsal skin that is immobilized by surgically implanted titanium frames, allowing the skin microvasculature to be visualized. We describe a detailed protocol for surgical implantation of the dorsal window chamber which enables researchers to perform the window chamber implantation surgery. We further describe subsequent wide-field functional imaging of the chamber to obtain hemodynamic information in the form of blood oxygenation and blood flow on a cm size region of interest. Optical imaging techniques, such as intravital microscopy, have been applied extensively to the dorsal window chamber to study microvascular-related disease and conditions. Due to the limited field of view of intravital microscopy, detailed hemodynamic information typically is acquired from small regions of interest, typically on the order of hundreds of μm. The wide-field imaging techniques described herein complement intravital microscopy, allowing researchers to obtain hemodynamic information at both microscopic and macroscopic spatial scales. Compared with intravital microscopy, wide-field functional imaging requires simple instrumentation, is inexpensive, and can give detailed metabolic information over a wide field of view.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.