ArticleBehavioral neuroscience2011
Social regulation of serotonin in the auditory midbrain.
Article in Behavioral neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Non-sensory Influences on Auditory Learning and Plasticity.Journal of the Association for Research in Otolaryngology : JARO · 2022Review
- Neurophysiological investigation of auditory intensity dependence in patients with Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- 5-HT1A Receptors Alter Temporal Responses to Broadband Vocalizations in the Mouse Inferior Colliculus Through Response Suppression.Frontiers in neural circuits · 2021Article
- Silence, Solitude, and Serotonin: Neural Mechanisms Linking Hearing Loss and Social Isolation.Brain sciences · 2020Review
- Serotonergic modulation across sensory modalities.Journal of neurophysiology · 2020Review
- Behavioral Animal Model of the Emotional Response to Tinnitus and Hearing Loss.Journal of the Association for Research in Otolaryngology : JARO · 2018Article
- Putting it in Context: Linking Auditory Processing with Social Behavior Circuits in the Vertebrate Brain.Integrative and comparative biology · 2017Review
- Stability and plasticity in neural encoding of linguistically relevant pitch patterns.Journal of neurophysiology · 2017Article
- Serotonin modulates response properties of neurons in the dorsal cochlear nucleus of the mouse.Hearing research · 2017Article
- Serotonin, estrus, and social context influence c-Fos immunoreactivity in the inferior colliculus.Behavioral neuroscience · 2016Article
- Socially induced serotonergic fluctuations in the male auditory midbrain correlate with female behavior during courtship.Journal of neurophysiology · 2016Article
- Behavioral effects of social challenges and genomic mechanisms of social priming: What's testosterone got to do with it?Current zoology · 2014Article
- Context-dependent fluctuation of serotonin in the auditory midbrain: the influence of sex, reproductive state and experience.The Journal of experimental biology · 2014Article
- From behavioral context to receptors: serotonergic modulatory pathways in the IC.Frontiers in neural circuits · 2012Article
- Plasticity of serotonergic innervation of the inferior colliculus in mice following acoustic trauma.Hearing research · 2012Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The neuromodulator serotonin regulates auditory processing and can increase within minutes in response to stimuli like broadband noise as well as nonauditory stressors. Little is known about the serotonergic response in the auditory system to more natural stimuli such as social interactions. Using carbon-fiber voltammetry, we measured extracellular serotonin in the auditory midbrain of resident male mice during encounters with a male intruder. Serotonin increased in the inferior colliculus (IC) over the course of a 15 minute interaction, but not when mice were separated with a perforated barrier. Several behaviors, including the amount of immobility and anogenital investigation performed by the resident, were correlated with the serotonergic response. Multiple intrinsic factors associated with individual mice also correlated with the serotonergic response. One of these was age: older mice had smaller serotonergic responses to the social interaction. In a second interaction, individual identity predicted serotonergic responses that were highly consistent with those in the first interaction, even when mice were paired with different intruders. Serotonin was also significantly elevated in the second social interaction relative to the first, suggesting a role for social experience. These findings show that during social interaction, serotonin in the IC is influenced by extrinsic factors such as the directness of social interaction and intrinsic factors including age, individual identity, and experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.