ReviewCellular and molecular life sciences : CMLS2011
Lessons from common markers of tumor-initiating cells in solid cancers.
Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Colorectal adenoma stem-like cell populations: associations with adenoma characteristics and metachronous colorectal neoplasia.Cancer prevention research (Philadelphia, Pa.) · 2013Trial
- Molecular mechanisms and therapeutic strategies in overcoming chemotherapy resistance in cancer.Molecular biomedicine · 2025Review
- LncRNA PCAT6 is a predictor of poor prognosis of colorectal cancer.Journal of gastrointestinal oncology · 2024Article
- MiR-942-3p as a Potential Prognostic Marker of Gastric Cancer Associated with AR and MAPK/ERK Signaling Pathway.Current issues in molecular biology · 2022Article
- Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture.Scientific reports · 2022Article
- Article
- Identification of a subpopulation of long-term tumor-initiating cells in colon cancer.Bioscience reports · 2020Article
- Abnormal expression of ABCD3 is an independent prognostic factor for colorectal cancer.Oncology letters · 2020Article
- Rationales for the Use of Cancer Stem Cells Markers in the Staging of Papillary Thyroid Carcinoma.Journal of oncology · 2019Article
- A Five-microRNA Signature as Prognostic Biomarker in Colorectal Cancer by Bioinformatics Analysis.Frontiers in oncology · 2019Article
- Article
- CBP501 suppresses macrophage induced cancer stem cell like features and metastases.Oncotarget · 2017Article
- Human mesenchymal stem cells preferentially migrate toward highly oncogenic human hepatocellular carcinoma cells with activated EpCAM signaling.Oncotarget · 2017Article
- Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion.Oncotarget · 2017Review
- ALDH1 and podoplanin expression patterns predict the risk of malignant transformation in oral leukoplakia.Oncology letters · 2017Article
- Pancreatic cancer stem cell markers and exosomes - the incentive push.World journal of gastroenterology · 2016Review
- Palmitoylated claudin7 captured in glycolipid-enriched membrane microdomains promotes metastasis via associated transmembrane and cytosolic molecules.Oncotarget · 2016Article
- Near infrared fluorescent nanoparticles based on hyaluronic acid: Self-assembly, optical properties, and cell interaction.Acta biomaterialia · 2016Article
- Interplay between Cellular and Molecular Inflammatory Mediators in Lung Cancer.Mediators of inflammation · 2016Review
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumor-initiating cells (TICs) have emerged as the driving force of carcinomas, which appear as hierarchically structured. TICs as opposed to the tumor bulk display tumor forming potential, which is linked to a certain degree of self-renewal and differentiation, both major features of stem cells. Markers such as CD44, CD133, CD24, EpCAM, CD166, Lgr5, CD47, and ALDH have been described, which allow for the prospective enrichment of TICs. It is conspicuous that the same markers allow for an enrichment of TICs in various entities and, on the other hand, that different combinations of these markers were independently reported for the same tumor entity. Potential functions of these markers in the regulation of TIC phenotypes remained somewhat neglected although they might give insights in common molecular themes of TICs. The present review discusses major TIC markers with respect to their function and potential contributions to the tumorigenic phenotype of TICs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.