ArticleEuropean radiology2011
Cardiac involvement in Wegener's granulomatosis resistant to induction therapy.
Article in European radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Cardiac Magnetic Resonance Imaging Findings in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitides: A Systematic Review.ACR open rheumatology · 2025Review
- A 44-year-old man with recurrent ST-segment elevation: a case report of two presentations of Granulomatosis with Polyangiitis.European heart journal. Case reports · 2024Article
- An uncommon case of complete AV block.BMC cardiovascular disorders · 2022Article
- Prediction of subclinical left ventricular dysfunction by speckle-tracking echocardiography in patients with anti-neutrophil cytoplasmic antibody--associated vasculitis.Archives of rheumatology · 2022Article
- Article
- Cardiac imaging of a patient with unusual presentation of granulomatosis with polyangiitis: A case report and review of the literature.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Myocarditis: A Clinical Overview.Current cardiology reports · 2017Review
- T1 and T2 mapping for evaluation of myocardial involvement in patients with ANCA-associated vasculitides.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017Article
- Cardiac involvement in primary systemic vasculitis and potential drug therapies to reduce cardiovascular risk.Rheumatology international · 2017Review
- Cardiac Involvement in Granulomatosis with Polyangiitis.The Journal of rheumatology · 2015Article
- Standard and feature tracking magnetic resonance evidence of myocardial involvement in Churg-Strauss syndrome and granulomatosis with polyangiitis (Wegener's) in patients with normal electrocardiograms and transthoracic echocardiography.The international journal of cardiovascular imaging · 2013Article
- Right ventricular cardiovascular magnetic resonance imaging: normal anatomy and spectrum of pathological findings.Insights into imaging · 2013Article
- Asymptomatic intracardiac mass in a 14-year-old girl with granulomatosis with polyangiitis: Case report.Pediatric rheumatology online journal · 2012Article
- Granulomatosis with polyangiitis in childhood.Current rheumatology reports · 2012Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of the study was to assess cardiac involvement in patients with Wegener's granulomatosis (WG), who failed to achieve remission following >6 months induction therapy for life or organ threatening disease.
methodsEleven WG patients (eight males, mean age 47 ± 13 years), who failed to achieve remission despite >6 months induction therapy, underwent transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR).
resultsCardiac involvement was present in 9 (82%) patients. Regional wall motion abnormalities were found in two individuals, but none had left ventricular (LV) ejection fraction <50%. Nine patients had late gadolinium enhancement (LGE) lesions involving LV myocardium and right ventricle free wall was involved in four patients. LGE lesions were found in subepicardial, midwall and subendocardial LV myocardial layers. CMR revealed myocarditis in six patients. Patients with myocarditis had a higher number of LV segments with LGE (5.2 ± 3.4 vs 1.0 ± 1.2, p = 0.03) and more frequent diastolic dysfunction by TTE (5 vs 0, p = 0.02) than those without. Pericardial effusion was observed in five patients, while localized pericardial thickening in six patients.
conclusionsIn WG resistant to >6 months induction therapy cardiac involvement is frequent and is characterized by foci of LGE lesions and signs of myocardial inflammatory process.
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