Evidence map›Paper›PMID 21786075›Full record

ArticleJournal of neurovirology2011

Progressive multifocal leukoencephalopathy associated with isolated CD8+ T-lymphocyte deficiency mimicking tumefactive MS.

Jennifer L McGuire, Vera Fridman, Christian Wüthrich, Igor J Koralnik, Dina Jacobs

Abstract readCase Reports
In one paragraph

Article in Journal of neurovirology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Controversies in neuroimmunology: Multiple sclerosis and other demyelinating disordersBiomedica : revista del Instituto Nacional de Salud · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer L McGuireDivision of Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA 19146, USA. mcguirej@email.chop.edu
Vera Fridman
Christian Wüthrich
Igor J Koralnik
Dina Jacobs

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Daniel Lingwood · 2004 to 2026
$94.4M
Role of Inflammation in Progressive Multifocal LeukoencephalopathyR01NS047029 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI KORALNIK, IGOR J. · 2004 to 2018
$6.4M
Neurologic Clinical Epidemiology Training ProgramT32NS061779 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Andrea Lauren Christman Schneider, Allison Willis · 2008 to 2026
$4.6M
CELLULAR IMMUNITY TO JC VIRUS IN AIDS ASSOCIATED PMLR01NS041198 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KORALNIK, IGOR J. · 2001 to 2009
$3.3M
Translational applications of Progressive Multifocal Leukoencephalopathy studiesK24NS060950 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KORALNIK, IGOR J. · 2008 to 2012
$707k
Cellular Immunity to JC Virus in AIDS-Associated Progressive Multifocal LeukoenceR56NS041198 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KORALNIK, IGOR J. · 2010 to 2010
$435k
NIAID NIH HHS P30 AI060354NINDS NIH HHS K24 NS 060950NINDS NIH HHS K24 NS060950NINDS NIH HHS R01 NS041198NINDS NIH HHS R01 NS047029NINDS NIH HHS R56 NS041198NINDS NIH HHS T32 NS061779NINDS NIH HHS T32-NS061779
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedBrainCD8-Positive T-LymphocytesFemaleHumansJC VirusLeukoencephalopathy, Progressive MultifocalLymphopeniaMagnetic Resonance ImagingMefloquineMianserinMirtazapineMultiple SclerosisNeuroimagingReference ValuesTreatment OutcomeMefloquineMianserinMirtazapine

Identifiers

PMID21786075
PMCPMC3204182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.