ArticleInternational journal of legal medicine2011
An efficient multiplex genotyping approach for detecting the major worldwide human Y-chromosome haplogroups.
Article in International journal of legal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- UYSD: a novel data repository accessible via public website for worldwide population frequencies of Y-SNP haplogroups.European journal of human genetics : EJHG · 2025Article
- Forensic DNA phenotyping: a review on SNP panels, genotyping techniques, and prediction models.Forensic sciences research · 2025Review
- Review
- Forensic biogeographical ancestry inference: recent insights and current trends.Genes & genomics · 2023Review
- Estimating Y-Str Mutation Rates and Tmrca Through Deep-Rooting Italian Pedigrees.Scientific reports · 2019Article
- Forensic use of Y-chromosome DNA: a general overview.Human genetics · 2017Review
- Forensically relevant SNaPshotInternational journal of legal medicine · 2017Review
- Article
- Inferring population structure and relationship using minimal independent evolutionary markers in Y-chromosome: a hybrid approach of recursive feature selection for hierarchical clustering.Nucleic acids research · 2014Article
- Genetic genealogy reveals true Y haplogroup of House of Bourbon contradicting recent identification of the presumed remains of two French Kings.European journal of human genetics : EJHG · 2014Article
- Partial AZFc duplications not deletions are associated with male infertility in the Yi population of Yunnan Province, China.Journal of Zhejiang University. Science. B · 2013Article
- First all-in-one diagnostic tool for DNA intelligence: genome-wide inference of biogeographic ancestry, appearance, relatedness, and sex with the Identitas v1 Forensic Chip.International journal of legal medicine · 2013Article
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3 authors.
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Abstract
The Y chromosome is paternally inherited and therefore serves as an evolutionary marker of patrilineal descent. Worldwide DNA variation within the non-recombining portion of the Y chromosome can be represented as a monophyletic phylogenetic tree in which the branches (haplogroups) are defined by at least one SNP. Previous human population genetics research has produced a wealth of knowledge about the worldwide distribution of Y-SNP haplogroups. Here, we apply previous and very recent knowledge on the Y-SNP phylogeny and Y-haplogroup distribution by introducing two multiplex genotyping assays that allow for the hierarchical detection of 28 Y-SNPs defining the major worldwide Y haplogroups. PCR amplicons were kept small to make the method sensitive and thereby applicable to DNA of limited amount and/or quality such as in forensic settings. These Y-SNP assays thus form a valuable tool for researchers in the fields of forensic genetics and genetic anthropology to infer a man's patrilineal bio-geographic ancestry from DNA.
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