Evidence map›Paper›PMID 21785892›Full record

Trial reportMaternal and child health journal2011

Understanding the association of biomedical, psychosocial and behavioral risks with adverse pregnancy outcomes among African-Americans in Washington, DC.

Michele Kiely, Ayman A E El-Mohandes, Marie G Gantz, Dhuly Chowdhury, Jutta S Thornberry, M Nabil El-Khorazaty

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Maternal and child health journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Online decision aids for contraceptive choices in women with chronic conditions: A systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Intimate Partner Violence: A Risk Factor for Gestational Diabetes.International journal of environmental research and public health · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Adult Cigarette Smokers at Highest Risk for Concurrent Alternative Tobacco Product Use Among a Racially/Ethnically and Socioeconomically Diverse Sample.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michele KielyDivision of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver NICHD/NIH/HHS, 6100 Executive Blvd, Rockville, MD 20852-7510, USA. kielym@nih.gov
Ayman A E El-Mohandes
Marie G Gantz
Dhuly Chowdhury
Jutta S Thornberry
M Nabil El-Khorazaty

Funding

NIH DC INITIATIVE TO REDUCE INFANT MORTALITYU18HD031206 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI EL-KHORAZATY, NABIL · 1993 to 2003
$6.0M
Reduction of Tobacco Exposure in Pregnancy and InfancyU10HD036104 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI PERRY, DAVID CARTER · 2004 to 2009
$4.7M
Cooperative Perinatal Studies and InterventionsU10HD030445 · NICHD · GEORGETOWN UNIVERSITY · PI SUBRAMANIAN, SIVA · 2004 to 2009
$4.3M
NIH D.C. INITIATIVE TO REDUCE INFANT MORTALITYU18HD031919 · NICHD · HOWARD UNIVERSITY · PI JOHNSON, ALLAN ALEXANDER · 1993 to 2003
$3.8M
COOPERATIVE PERINATAL STUDIES AND INTERVENTIONSU18HD030445 · NICHD · GEORGETOWN UNIVERSITY · PI SIVASUBRAMANIAN, KOLINJAVADI N · 1992 to 2003
$3.7M
NIH D.C. INITIATIVE TO REDUCE INFANT MORTALITYU18HD036104 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI EL-MOHANDES, AYMAN A · 1998 to 2003
$2.7M
COOPERATIVE PERINATAL STUDIES AND INTERVENTIONSU18HD030447 · NICHD · CHILDREN'S NATIONAL MEDICAL CENTER · PI JOSEPH, JILL G. · 1992 to 2003
$1.7M
Intramural NIH HHSNICHD NIH HHS 3U18HD030445NICHD NIH HHS 3U18HD030447NICHD NIH HHS 3U18HD03919NICHD NIH HHS 5U18HD036104NICHD NIH HHS 5U18HD31206NICHD NIH HHS U10 HD030445NICHD NIH HHS U10 HD036104NICHD NIH HHS U18 HD030445NICHD NIH HHS U18 HD030447NICHD NIH HHS U18 HD031206NICHD NIH HHS U18 HD031919NICHD NIH HHS U18 HD036104
6 · The paper itself

Abstract

This study investigates the relationship between adverse pregnancy outcomes in high-risk African American women in Washington, DC and sociodemographic risk factors, behavioral risk factors, and the most common and interrelated medical conditions occurring during pregnancy: diabetes, hypertension, preeclampsia, and Body Mass Index (BMI). Data are from a randomized controlled trial conducted in 6 prenatal clinics. Women in their 1st or 2nd trimester were screened for behavioral risks (smoking, environmental tobacco smoke exposure, depression, and intimate partner violence) and demographic eligibility. 1,044 were eligible, interviewed and followed through their pregnancies. Classification and Regression Trees (CART) methodology was used to: (1) explore the relationship between medical and behavioral risks (reported at enrollment), sociodemographic factors and pregnancy outcomes; (2) identify the relative importance of various predictors of adverse pregnancy outcomes; and (3) characterize women at the highest risk of poor pregnancy outcomes. The strongest predictors of poor outcomes were prepregnancy BMI, preconceptional diabetes, employment status, intimate partner violence, and depression. In CART analysis, preeclampsia was the first splitter for low birthweight; preconceptional diabetes was the first splitter for preterm birth (PTB) and neonatal intensive care admission; BMI was the first splitter for very PTB, large for gestational age, Cesarean section and perinatal death; employment was the first splitter for miscarriage. Preconceptional factors strongly influence pregnancy outcomes. For many of these women, the high risks they brought into pregnancy were more likely to impact their pregnancy outcomes than events during pregnancy.

Indexed as

AdultBlack or African AmericanDistrict of ColumbiaFemaleHealth BehaviorHumansInterviews as TopicPregnancyPregnancy ComplicationsPregnancy OutcomeRegression AnalysisRisk FactorsSocioeconomic FactorsYoung Adult

Identifiers

PMID21785892
PMCPMC3220795

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.