ArticlePediatric radiology2011
Comparison of MR enterography and histopathology in the evaluation of pediatric Crohn disease.
Article in Pediatric radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Pooled it
- Diagnostic Accuracy of Non-Invasive Imaging for Detection of Colonic Inflammation in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2021Review
- Capsule Endoscopy Complements Magnetic Resonance Enterography and Endoscopy in Evaluating Small Bowel Crohn's Disease.Journal of the Canadian Association of Gastroenterology · 2020Article
- Article
- Can diffusion weighting replace gadolinium enhancement in magnetic resonance enterography for inflammatory bowel disease in children?Pediatric radiology · 2018Article
- Magnetic resonance enterography evaluation of Crohn disease activity and mucosal healing in young patients.Pediatric radiology · 2018Review
- Colonic inflammation in pediatric inflammatory bowel disease: detection with magnetic resonance enterography.Pediatric radiology · 2017Article
- Assessing pediatric ileocolonic Crohn's disease activity based on global MR enterography scores.European radiology · 2017Article
- Ultrasound and MRI predictors of surgical bowel resection in pediatric Crohn disease.Pediatric radiology · 2017Article
- MR enterography: how to deliver added value.Pediatric radiology · 2016Review
- Prospective evaluation of free-breathing diffusion-weighted imaging for the detection of inflammatory bowel disease with MR enterography in childhood population.The British journal of radiology · 2016Article
- MRI diffusion-weighted imaging (DWI) in pediatric small bowel Crohn disease: correlation with MRI findings of active bowel wall inflammation.Pediatric radiology · 2013Article
- MR enterography in children: Principles, technique, and clinical applications.The Indian journal of radiology & imaging · 2013Article
- Small-bowel MRI in children and young adults with Crohn disease: retrospective head-to-head comparison of contrast-enhanced and diffusion-weighted MRI.Pediatric radiology · 2013Article
- MRI in Crohn's disease--current and future clinical applications.Nature reviews. Gastroenterology & hepatology · 2011Review
- Magnetic resonance enterography and wireless capsule endoscopy in the evaluation of patients with inflammatory bowel disease.Clinical imagingArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile MR enterography (MRE) is commonly used to identify segments of bowel affected by Crohn disease in children, there is little data to support this practice.
objectiveTo assess the ability of MRE to identify segments of small bowel and colon affected by pediatric Crohn disease using histopathology as the reference standard. MATERIALS AND
methodsPediatric MRE examinations performed between April 2009 and December 2010 were identified. Subjects were excluded if they did not have Crohn disease, if they had Crohn disease but no correlative histopathology within 2 months of imaging, or if they had undergone prior bowel resection. Pertinent MRE and histopathology reports were reviewed, and normal and abnormal bowel segments were documented.
resultsThirty-two pediatric MRE examinations were identified with correlative histopathology. MRE had an overall sensitivity of 94% for detecting the presence of Crohn disease, in general. At the bowel segmental level, MRE had a sensitivity of 66%, specificity of 90%, positive predictive value of 85% and negative predictive value of 76%. The terminal ileum was abnormal by MRE in 11 of 15 (73%) subjects lacking a diagnostic biopsy of this bowel segment.
conclusionMRE successfully identifies small bowel and colon segments affected by pediatric Crohn disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.