Evidence map›Paper›PMID 21785729›Full record

ArticleJournal of aging research2011

Alcohol consumption and risk of all-cause and cardiovascular disease mortality in men.

Erin K Howie, Xuemei Sui, Duck-Chul Lee, Steven P Hooker, James R Hébert, Steven N Blair

Abstract read
In one paragraph

Article in Journal of aging research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erin K HowieDepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Xuemei Sui
Duck-Chul Lee
Steven P Hooker
James R Hébert
Steven N Blair

Funding

Biomedical-Behavioral Interface: Prevention and Developmental Sciences TrainingT32GM081740 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PRINZ, RONALD J · 2008 to 2022
$4.5M
Impact of Physical Fitness and Exercise on HealthR37AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 2002 to 2005
$2.7M
CORONARY ARTERY CALCIUM, EXERCISE TESTS, AND CHD OUTCOMER01HL062508 · NHLBI · COOPER INSTITUTE · PI LAMONTE, MICHAEL J · 1999 to 2004
$2.5M
IMPACT OF PHYSICAL FITNESS &EXERCISE ON HEALTHR01AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 1986 to 2001
$1.1M
Expanding Mentoring Capacity in High-Risk PopulationsK05CA136975 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HEBERT, JAMES R · 2009 to 2013
$801k
Understanding Patterns of Change in Obesity and Physical Activity in AdultsR21DK088195 · NIDDK · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SUI, XUEMEI · 2010 to 2011
$397k
NCI NIH HHS K05 CA136975NHLBI NIH HHS R01 HL062508NIA NIH HHS R01 AG006945NIA NIH HHS R37 AG006945NIDDK NIH HHS R21 DK088195NIGMS NIH HHS T32 GM081740
6 · The paper itself

Abstract

This study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n = 31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, and aerobic fitness, there were no significant differences in risk of all-cause mortality across alcohol intake groups. Risk of CVD mortality was reduced 29% in quartile 1 (HR = 0.71, 95% confidence interval (CI): 0.53, 0.95) and 25% in quartile 2 (HR = 0.75, 95% CI: 0.58, 0.98). The amount of alcohol consumed to achieve this risk reduction was <6 drinks/week; less than the amount currently recommended. The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitude of association. Future research is needed to validate the current public health recommendations for alcohol consumption.

Identifiers

PMID21785729
PMCPMC3140194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.