Evidence map›Paper›PMID 21785567›Full record

ArticleJournal of biomedicine & biotechnology2011

Dampening Host Sensing and Avoiding Recognition in Pseudomonas aeruginosa Pneumonia.

Cristina Cigana, Nicola Ivan Lorè, Maria Lina Bernardini, Alessandra Bragonzi

Open access · hybridAbstract read
In one paragraph

Article in Journal of biomedicine & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Effects of Inhaled Corticosteroids on the Innate Immunological Response toInternational journal of molecular sciences · 2022
    Article
  4. Review
  5. Review
  6. International journal of molecular sciences · 2021
    Review
  7. Article
  8. Article
  9. Frontiers in immunology · 2020
    Article
  10. Proteomic Analysis of Vesicle-ProducingFrontiers in microbiology · 2020
    Article
  11. Article
  12. Comparative Analysis of Peptidoglycans FromFrontiers in microbiology · 2019
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Host-pathogen interplay in the respiratory environment of cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2015
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Cristina CiganaInfections and Cystic Fibrosis Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, 20132 Milano, Italy.
Nicola Ivan Lorè
Maria Lina Bernardini
Alessandra Bragonzi
Vita-Salute San Raffaele University · ITIstituto Pasteur · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa is an opportunistic pathogen and causes a wide range of acute and chronic infections. P. aeruginosa infections are kept in check by an effective immune surveillance in the healthy host, while any imbalance or defect in the normal immune response can manifest in disease. Invasive acute infection in the immunocompromised patients is mediated by potent extracellular and cell bound bacterial virulence factors. Life-threatening chronic infection in cystic fibrosis patients is maintained by pathogenic variants that contribute to evade detection and clearance by the immune system. Here, we reviewed the molecular basis of receptor-mediated recognition of P. aeruginosa and their role in initiating inflammation and the colonization. In addition, the consequence of the P. aeruginosa genetic adaptation for the antibacterial defence and the maintaining of chronic infection are discussed.

Identifiers

PMID21785567
PMCPMC3139209
OpenAlexW1969959057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.