Evidence map›Paper›PMID 21785353›Full record

ReviewCurrent opinion in otolaryngology & head and neck surgery2011

Auditory mechanics of the tectorial membrane and the cochlear spiral.

Núria Gavara, Daphne Manoussaki, Richard S Chadwick

Abstract readReview
In one paragraph

Review in Current opinion in otolaryngology & head and neck surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.Frontiers in cell and developmental biology · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Longitudinal spread of mechanical excitation through tectorial membrane traveling waves.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  9. Basilar membrane and tectorial membrane stiffness in the CBA/CaJ mouse.Journal of the Association for Research in Otolaryngology : JARO · 2014
    Article
  10. Article
  11. Article
  12. Article
  13. Electrokinetic properties of the mammalian tectorial membrane.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  14. Evolutionary paths to mammalian cochleae.Journal of the Association for Research in Otolaryngology : JARO · 2012
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Núria GavaraAuditory Mechanics Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland 20892, USA.
Daphne Manoussaki
Richard S Chadwick

Funding

Biomechanics Of Cochlear Fine TuningZIADC000033 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI CHADWICK, RICHARD S. · 2009 to 2019
$8.4M
Training Program in Hearing and BalanceT32DC000033 · NIDCD · UNIVERSITY OF WASHINGTON · PI WERNER, LYNNE A. · 1991 to 2015
$3.9M
BIOMECHANICS OF COCHLEAR FINE TUNINGZ01DC000033 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI CHADWICK, RICHARD S. · 1996 to 2008
$1.2M
Intramural NIH HHS Z01 DC000033Intramural NIH HHS ZIA DC000033NIDCD NIH HHS DC00033-15NIDCD NIH HHS T32 DC000033
6 · The paper itself

Abstract

purpose of reviewThis review is timely and relevant because new experimental and theoretical findings suggest that cochlear mechanics from the nanoscale to the macroscale are affected by the mechanical properties of the tectorial membrane and the cochlea's spiral shape. RECENT

findingsMain tectorial membrane themes addressed in this review are composition and morphology, nanoscale mechanical interactions with the outer hair cell bundle, macroscale longitudinal coupling, fluid interaction with inner hair cell bundles, and macroscale dynamics and waves. Main cochlear spiral themes are macroscale, low-frequency energy focusing and microscale organ of Corti shear gain. SUMMARY: Recent experimental and theoretical findings reveal exquisite sensitivity of cochlear mechanical performance to tectorial membrane structural organization, mechanics, and its positioning with respect to hair bundles. The cochlear spiral geometry is a major determinant of low-frequency hearing. These findings suggest a number of important research directions.

Indexed as

AnimalsAuditory PathwaysBiomechanical PhenomenaCochleaCochlear Microphonic PotentialsHair Cells, AuditoryHearingHumansTectorial Membrane

Identifiers

PMID21785353
PMCPMC3327783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.