ArticleJournal of bacteriology2011
Characterization of the Fur regulon in Pseudomonas syringae pv. tomato DC3000.
Article in Journal of bacteriology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 56 citations in OpenAlex.
- Machine learning uncovers themSystems · 2023Article
- Meddling with Metal Sensors: Fur-Family Proteins as Signaling Hubs.Journal of bacteriology · 2023Review
- The Burkholderia cenocepacia iron starvation σ factor, OrbS, possesses an on-board iron sensor.Nucleic acids research · 2022Article
- Virulence-related regulatory network ofComputational and structural biotechnology journal · 2022Review
- In planta transcriptomics reveals conflicts between pattern-triggered immunity and the AlgU sigma factor regulon.PloS one · 2022Article
- The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans.PLoS pathogens · 2021Article
- Vfr targets promoter of genes encoding methyl-accepting chemotaxis protein inBiochemistry and biophysics reports · 2021Article
- New evolving strategies revealed by transcriptomic analysis of a furMicrobial biotechnology · 2020Article
- Elucidating the Regulon of a FurFrontiers in microbiology · 2020Article
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- CaJournal of bacteriology · 2018Article
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- Metal-responsive promoter DNA compaction by the ferric uptake regulator.Nature communications · 2016Article
- The metabolic regulator CodY links Listeria monocytogenes metabolism to virulence by directly activating the virulence regulatory gene prfA.Molecular microbiology · 2015Article
- Functional genomics of tomato: opportunities and challenges in post-genome NGS era.Journal of biosciences · 2014Review
- The iron stimulon and fur regulon of Geobacter sulfurreducens and their role in energy metabolism.Applied and environmental microbiology · 2014Article
- COV2HTML: a visualization and analysis tool of bacterial next generation sequencing (NGS) data for postgenomics life scientists.Omics : a journal of integrative biology · 2014Article
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Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
The plant pathogen Pseudomonas syringae pv. tomato DC3000 (DC3000) is found in a wide variety of environments and must monitor and respond to various environmental signals such as the availability of iron, an essential element for bacterial growth. An important regulator of iron homeostasis is Fur (ferric uptake regulator), and here we present the first study of the Fur regulon in DC3000. Using chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq), 312 chromosomal regions were highly enriched by coimmunoprecipitation with a C-terminally tagged Fur protein. Integration of these data with previous microarray and global transcriptome analyses allowed us to expand the putative DC3000 Fur regulon to include genes both repressed and activated in the presence of bioavailable iron. Using nonradioactive DNase I footprinting, we confirmed Fur binding in 41 regions, including upstream of 11 iron-repressed genes and the iron-activated genes encoding two bacterioferritins (PSPTO_0653 and PSPTO_4160), a ParA protein (PSPTO_0855), and a two-component system (TCS) (PSPTO_3382 to PSPTO_3380).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.