ArticleThe Journal of pediatrics2011
Racial/ethnic and sex differences in the ability of metabolic syndrome criteria to predict elevations in fasting insulin levels in adolescents.
Article in The Journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Heritability of the Severity of the Metabolic Syndrome in Whites and Blacks in 3 Large Cohorts.Circulation. Cardiovascular genetics · 2017Pooled it
- Use of a Metabolic Syndrome SeverityDiabetes care · 2018Trial
- Cross-sectional association of fitness, fatness, and dyslipidemia with metabolic syndrome in youth.World journal of clinical pediatrics · 2025Article
- Investigating family history of diabetes as a predictor of fasting insulin and fasting glucose activity in a sample of healthy weight adults.Acta diabetologica · 2023Article
- Breakfast Consumption May Improve Fasting Insulin, HOMA-IR, and HbA1c Levels in Predominately Low-Income, Hispanic Children 7-12 Years of Age.Nutrients · 2022Article
- Severity of the metabolic syndrome as a predictor of prediabetes and type 2 diabetes in first degree relatives of type 2 diabetic patients: A 15-year prospective cohort study.World journal of diabetes · 2020Article
- Associations of a metabolic syndrome severity score with coronary heart disease and diabetes in fasting vs. non-fasting individuals.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2020Article
- Enhanced Myeloid Leukocytes in Obese Children and Adolescents at Risk for Metabolic Impairment.Frontiers in endocrinology · 2020Article
- Metabolic syndrome severity and lifestyle factors among adolescents.Minerva pediatrica · 2018Review
- Assessing Baseline and Temporal Changes in Cardiometabolic Risk Using Metabolic Syndrome Severity and Common Risk Scores.Journal of the American Heart Association · 2018Article
- Use of BMI as the marker of adiposity in a metabolic syndrome severity score: Derivation and validation in predicting long-term disease outcomes.Metabolism: clinical and experimental · 2018Article
- Geographical variation in the prevalence of obesity, metabolic syndrome, and diabetes among US adults.Nutrition & diabetes · 2018Article
- Metabolic syndrome severity is significantly associated with future coronary heart disease in Type 2 diabetes.Cardiovascular diabetology · 2018Article
- Assessing the added predictive ability of a metabolic syndrome severity score in predicting incident cardiovascular disease and type 2 diabetes: the Atherosclerosis Risk in Communities Study and Jackson Heart Study.Diabetology & metabolic syndrome · 2018Article
- Article
- Correlation of metabolic syndrome severity with cardiovascular health markers in adolescents.Metabolism: clinical and experimental · 2017Article
- Clinical utility of metabolic syndrome severity scores: considerations for practitioners.Diabetes, metabolic syndrome and obesity : targets and therapy · 2017Review
- Progression of Metabolic Syndrome Severity During the Menopausal Transition.Journal of the American Heart Association · 2016Article
- Article
- A metabolic syndrome severity score to estimate risk in adolescents and adults: current evidence and future potential.Expert review of cardiovascular therapy · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate racial/ethnic and sex differences in the relationship between metabolic syndrome (MetS) diagnosis and fasting insulin in adolescents. STUDY
designWe analyzed data from the National Health and Nutrition Evaluation Survey 1999-2008 for 3693 non-Hispanic-white, non-Hispanic-black, and Hispanic adolescents (12 to 19 years of age). We used linear regression to evaluate differences in fasting insulin levels between those with and without an adolescent adaptation of ATPIII-MetS in a sex- and race/ethnicity-specific basis.
resultsFemales had higher insulin levels than males, and non-Hispanic blacks and Hispanics had higher levels than non-Hispanic whites. Adolescents with MetS had higher insulin levels than those without MetS. The difference in insulin levels between those with and without MetS was greater in non-Hispanic blacks than in non-Hispanic whites (P < .05) but not Hispanics (P = .10). The sensitivity of MetS in detecting elevated insulin levels was lower in non-Hispanic blacks and females than in other ethnicities and males, respectively. Correlations between insulin and individual MetS components were similar among ethnicities.
conclusionMetS diagnosis performed more poorly in predicting elevated insulin levels in non-Hispanic blacks and in females. These data support the hypothesis that non-Hispanic blacks do not meet current criteria for MetS until they have reached a more advanced degree of insulin resistance.
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Registered trials
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