ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2011
The role of maternal early-life and later-life risk factors on offspring low birth weight: findings from a three-generational study.
Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Parental Preconception Adversity and Offspring Health in African Americans: A Systematic Review of Intergenerational Studies.Trauma, violence & abuse · 2023Pooled it
- Black/White disparities in low birth weight across maternal trajectories of social mobility in South Carolina.Social science & medicine (1982) · 2025Article
- Maternal exposure to childhood maltreatment and adverse birth outcomes.Scientific reports · 2023Article
- Racial/ethnic disparities in severe maternal morbidity: An intersectional lifecourse approach.Annals of the New York Academy of Sciences · 2022Article
- Patterns of adverse childhood experiences and associations with prenatal substance use and poor infant outcomes in a multi-country cohort of mothers: a latent class analysis.BMC pregnancy and childbirth · 2022Article
- Adverse Childhood Experiences and Complex Post-traumatic Stress in Pregnant Teens: A Pilot Study.Maternal and child health journal · 2021Article
- The Impact of Early-Life Exposures on Women's Reproductive Health in Adulthood.Current epidemiology reports · 2021Review
- Ceremonial Ayahuasca in Amazonian Retreats-Mental Health and Epigenetic Outcomes From a Six-Month Naturalistic Study.Frontiers in psychiatry · 2021Article
- Intergenerational associations of adverse birth outcomes: A surveillance report.Preventive medicine reports · 2020Article
- Intergenerational congruence in adolescent onset of alcohol, tobacco, and marijuana use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020Article
- Exposure to childhood abuse is associated with human sperm DNA methylation.Translational psychiatry · 2018Article
- Intergenerational pathways linking maternal early life adversity to offspring birthweight.Social science & medicine (1982) · 2018Article
- Theoretical Insights into Preconception Social Conditions and Perinatal Health: The Role of Place and Social Relationships.Population research and policy review · 2017Article
- Childhood maltreatment and inflammation among pregnant women with gestational diabetes mellitus: A pilot study.Obstetric medicine · 2017Article
- Maternal abuse history and reduced fetal heart rate variability: Abuse-related sleep disturbance is a mediator.Development and psychopathology · 2017Article
- Grandparents' Education and Infant Health: Pathways across Generations.Journal of marriage and the family · 2017Article
- Accounting for Life-Course Exposures in Epigenetic Biomarker Association Studies: Early Life Socioeconomic Position, Candidate Gene DNA Methylation, and Adult Cardiometabolic Risk.American journal of epidemiology · 2016Article
- Abuse in Childhood or Adolescence and Gestational Diabetes: A Retrospective Cohort Study.American journal of preventive medicine · 2016Article
- Infant Massage and Quality of Early Mother-Infant Interactions: Are There Associations with Maternal Psychological Wellbeing, Marital Quality, and Social Support?Frontiers in psychology · 2016Article
- Gestational age and newborn size according to parental social mobility: an intergenerational cohort study.Journal of epidemiology and community health · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThis study examined three research questions: (1) Is there an association between maternal early-life economic disadvantage and the birth weight of later-born offspring? (2) Is there an association between maternal abuse in childhood and the birth weight of later-born offspring? (3) To what extent are these early-life risks mediated through adolescent and adult substance use, mental and physical health status, and adult socioeconomic status (SES)?
methodsAnalyses used structural equation modeling to examine data from two longitudinal studies, which included three generations. The first generation (G1) and the second generation (G2) were enrolled in the Seattle Social Development Project (SSDP), and the third generation (G3) was enrolled in the SSDP Intergenerational Project. Data for the study (N = 136) focused on (G2) mothers enrolled in the SSDP and their children (G3).
resultsAnalyses revealed that G2 low childhood SES predicted G3 offspring birth weight. Early childhood abuse among G2 respondents predicted G3 offspring birth weight through a mediated pathway including G2 adolescent substance use and G2 prenatal substance use. Birth weight was unrelated to maternal adult SES, depression, or obesity.
conclusionsTo our knowledge, this is the first study to identify the effect of maternal early-life risks of low childhood SES and child maltreatment on later-born offspring birth weight. These findings have far-reaching effects on the cumulative risk associated with early-life economic disadvantage and childhood maltreatment. Such findings encourage policies and interventions that enhance child health at birth by taking the mother's own early-life and development into account.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.