Evidence map›Paper›PMID 21778817›Full record

ReviewVirulence

Bacterial interactions in dental biofilm.

Ruijie Huang, Mingyun Li, Richard L Gregory

Open access · goldAbstract readReview
In one paragraph

Review in Virulence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 197 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
197citing papers in PubMed, 5 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

197 citing papers in PubMed, 5 syntheses or guidelines pooled it, 484 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Peptide Designs for Use in Caries Management: A Systematic Review.International journal of molecular sciences · 2023
    Pooled it
  4. Klebsiella pneumoniae: an increasing threat to public health.Annals of clinical microbiology and antimicrobials · 2020
    Pooled it
  5. Pooled it
  6. Trial
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  9. Review
  10. TheApplied and environmental microbiology · 2026
    Article
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  12. Article
  13. Review
  14. Classification and Anti-Pathogens (Basel, Switzerland) · 2026
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

137 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Ruijie HuangDepartment of Oral Biology and Tobacco Cessation and Biobehavioral Center, School of Dentistry, Indiana University, Indianapolis, IN, USA.
Mingyun Li
Richard L Gregory
Indianapolis Zoo · USIndiana University · USState Key Laboratory of Oral Diseases

Funding

Lung Microbiome and Pulmonary Inflammation/Immunity in HIV InfectionU01HL098960 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI TWIGG, HOMER L, WEINSTOCK, GEORGE M · 2009 to 2013
$3.7M
High-performance Biocompatible GIC System with Permanent Antibacterial FunctionRC1DE020614 · NIDCR · INDIANA UNIVERSITY INDIANAPOLIS · PI XIE, DONG · 2009 to 2010
$797k
NHLBI NIH HHS HL098960NHLBI NIH HHS U01 HL098960NIDCR NIH HHS DE020614NIDCR NIH HHS RC1 DE020614
6 · The paper itself

Abstract

Biofilms are masses of microorganisms that bind to and multiply on a solid surface, typically with a fluid bathing the microbes. The microorganisms that are not attached but are free floating in an aqueous environment are termed planktonic cells. Traditionally, microbiology research has addressed results from planktonic bacterial cells. However, many recent studies have indicated that biofilms are the preferred form of growth of most microbes and particularly those of a pathogenic nature. Biofilms on animal hosts have significantly increased resistance to various antimicrobials compared to planktonic cells. These microbial communities form microcolonies that interact with each other using very sophisticated communication methods (i.e., quorum-sensing). The development of unique microbiological tools to detect and assess the various biofilms around us is a tremendously important focus of research in many laboratories. In the present review, we discuss the major biofilm mechanisms and the interactions among oral bacteria.

Indexed as

Bacterial Physiological PhenomenaMicrobial InteractionsAnimalsBacteriaBiofilmsHumansModels, BiologicalQuorum SensingTooth

Identifiers

PMID21778817
PMCPMC3322631
OpenAlexW2063051937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.