ReviewJournal of genetics and genomics = Yi chuan xue bao2011
Recent progress in the genetics of generalized vitiligo.
Review in Journal of genetics and genomics = Yi chuan xue bao, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 67 citations in OpenAlex.
- NLRP1 gene polymorphism rs2670660 is associated with vitiligo in the Pakistani population.Molecular biology reports · 2025Article
- Up-and-Coming Drugs for the Treatment of Vitiligo.Annals of dermatology · 2024Review
- Article
- Granzyme B Gene Polymorphisms Are Associated With Severe Non-segmental Vitiligo.The Journal of clinical and aesthetic dermatology · 2023Article
- Inducible Nitric Oxide Synthase iNOS-954-G>C and Ex16+14-C>T Gene Polymorphisms and Susceptibility to Vitiligo in the Saudi Population.Pharmacogenomics and personalized medicine · 2022Article
- A Rare Case of Congenital Vitiligo in a Neonate.The Journal of clinical and aesthetic dermatology · 2021Article
- Vitiligo, From Physiopathology to Emerging Treatments: A Review.Dermatology and therapy · 2020Review
- The role of IFIH1 gene rs1990760 and rs2111485 single-nucleotide polymorphisms in generalized vitiligo predispositionTurkish journal of medical sciences · 2019Article
- Clinical and Molecular Aspects of Vitiligo Treatments.International journal of molecular sciences · 2018Review
- Purified Mushroom Tyrosinase Induced Melanogenic Protein Expression in B16F10 Melanocytes: A Quantitative Densitometric Analysis.The open medicinal chemistry journal · 2018Article
- Meta-analysis of the association betweenOncotarget · 2017Article
- Liver X Receptor-α polymorphisms (rs11039155 and rs2279238) are associated with susceptibility to vitiligo.Meta gene · 2016Article
- Effect of Purified Mushroom Tyrosinase on Melanin Content and Melanogenic Protein Expression.Biotechnology research international · 2016Article
- Association analysis revealed one susceptibility locus for vitiligo with immune-related diseases in the Chinese Han population.Immunogenetics · 2015Article
- Polymorphisms in Toll-like receptor genes are associated with vitiligo.Frontiers in genetics · 2015Article
- The genetics of human skin disease.Cold Spring Harbor perspectives in medicine · 2014Review
- Current aspects of vitiligo genetics.Postepy dermatologii i alergologii · 2014Review
- Analysis of oxidative stress status, catalase and catechol-O-methyltransferase polymorphisms in Egyptian vitiligo patients.PloS one · 2014Article
- Whole exome sequencing identifies a mutation for a novel form of corneal intraepithelial dyskeratosis.Journal of medical genetics · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Vitiligo is an acquired disease characterized principally by patchy depigmentation of skin and overlying hair. Generalized vitiligo (GV), the predominant form of the disorder, results from autoimmune loss of melanocytes from affected regions. GV is a "complex trait", inherited in a non-Mendelian polygenic, multifactorial manner. GV is epidemiologically associated with other autoimmune diseases, both in GV patients and in their close relatives, suggesting that shared genes underlie susceptibility to this group of diseases. Early candidate gene association studies yielded a few successes, such as PTPN22, but most such reports now appear to be false-positives. Subsequent genomewide linkage studies identified NLRP1 and XBP1, apparent true GV susceptibility genes involved in immune regulation, and recent genome-wide association studies (GWAS) of GV in Caucasian and Chinese populations have yielded a large number of additional validated GV susceptibility genes. Together, these genes highlight biological systems and pathways that reach from the immune cells to the melanocyte, and provide insights into both disease pathogenesis and potential new targets for both treatment and even prevention of GV and other autoimmune diseases in genetically susceptible individuals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.