Evidence map›Paper›PMID 21777674›Full record

ReviewBiochimica et biophysica acta2012

Structural imaging in early pre-states of dementia.

Charles D Smith

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Oxidative stress in aging--matters of the heart and mind.International journal of molecular sciences · 2013
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Charles D SmithAlzheimer's Disease Center, Sanders-Brown Center on Aging, University of Kentucky, USA. csmith@mri.uky.edu

Funding

University of Kentucky Alzheimer's Disease Core Center - Biomarker CoreP30AG028383 · NIA · UNIVERSITY OF KENTUCKY · PI GOLD, BRIAN TIMOTHY, VAN ELDIK, LINDA J · 2006 to 2020
$23.3M
TRAINING AND INFORMATION TRANSFER COREP50AG005144 · NIA · UNIVERSITY OF KENTUCKY · PI MARKESBERY, WILLIAM R · 1985 to 2005
$8.9M
Detection of presymptomatic Alzheimer's disease by fMRIR01NS036660 · NINDS · UNIVERSITY OF KENTUCKY · PI SMITH, CHARLES DENNIS · 1997 to 2007
$1.6M
NIA NIH HHS P30 AG028383NIA NIH HHS P50 AG005144NIA NIH HHS P50 AG05144NINDS NIH HHS R01 NS036660PHS HHS R01-36660
6 · The paper itself

Abstract

In this review focus is on structural imaging in the Alzheimer's disease (AD) pre-states, particularly cognitively normal (CN) persons at future dementia risk. Findings in mild cognitive impairment (MCI) are described here only for comparison with CN. Cited literature evidence and commentary address issues of structural imaging alterations in CN that precede MCI and AD, regional patterns of such alterations, and the time relationship between structural imaging alterations and the appearance of symptoms of AD, issues relevant to the conduct of future AD prevention trials. This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease.

Indexed as

Alzheimer DiseaseBrainCognition DisordersCognitive DysfunctionHumansNeuroimaging

Identifiers

PMID21777674
PMCPMC3223541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.