ArticleJournal of visualized experiments : JoVE2011
Mouse bladder wall injection.
Article in Journal of visualized experiments : JoVE, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery.Translational oncology · 2025Article
- RNA-seq gene expression profiling of the bladder in a mouse model of urogenital schistosomiasis.bioRxiv : the preprint server for biology · 2024Article
- Evaluation of direct intramural injection to the bladder wall as a method for developing orthotopic tumor models.Animal models and experimental medicine · 2022Article
- Article
- Host tissue proteomics reveal insights into the molecular basis of Schistosoma haematobium-induced bladder pathology.PLoS neglected tropical diseases · 2022Article
- AIM2 inflammasome activation benefits the therapeutic effect of BCG in bladder carcinoma.Frontiers in pharmacology · 2022Article
- Interleukin-4 Signaling Plays a Major Role in Urogenital Schistosomiasis-Associated Bladder Pathogenesis.Infection and immunity · 2020Article
- IPSE, an abundant egg-secreted protein of the carcinogenic helminthInfectious agents and cancer · 2020Article
- Schistosoma haematobium cercarial infection alters subsequent systemic immune responses to eggs but has minimal impact on immune responses to egg injection of the bladder.Parasite immunology · 2019Article
- Understanding Urogenital Schistosomiasis-Related Bladder Cancer: An Update.Frontiers in medicine · 2018Review
- Development of Urinary Bladder Pre-Neoplasia byThe Korean journal of parasitology · 2017Article
- Schistosoma haematobium egg-induced bladder urothelial abnormalities dependent on p53 are modulated by host sex.Experimental parasitology · 2015Article
- Designer aminoglycosides prevent cochlear hair cell loss and hearing loss.The Journal of clinical investigation · 2015Article
- Macrophages are required for host survival in experimental urogenital schistosomiasis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015Article
- Sigma S-dependent antioxidant defense protects stationary-phase Escherichia coli against the bactericidal antibiotic gentamicin.Antimicrobial agents and chemotherapy · 2014Article
- Controversies and challenges in research on urogenital schistosomiasis-associated bladder cancer.Trends in parasitology · 2014Review
- Helminth-induced interleukin-4 abrogates invariant natural killer T cell activation-associated clearance of bacterial infection.Infection and immunity · 2014Article
- Minimally invasive establishment of murine orthotopic bladder xenografts.Journal of visualized experiments : JoVE · 2014Article
- Article
- An orthotopic bladder tumor model and the evaluation of intravesical saRNA treatment.Journal of visualized experiments : JoVE · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Mouse bladder wall injection is a useful technique to orthotopically study bladder phenomena, including stem cell, smooth muscle, and cancer biology. Before starting injections, the surgical area must be cleaned with soap and water and antiseptic solution. Surgical equipment must be sterilized before use and between each animal. Each mouse is placed under inhaled isoflurane anesthesia (2-5% for induction, 1-3% for maintenance) and its bladder exposed by making a midline abdominal incision with scissors. If the bladder is full, it is partially decompressed by gentle squeezing between two fingers. The cell suspension of interest is intramurally injected into the wall of the bladder dome using a 29 or 30 gauge needle and 1 cc or smaller syringe. The wound is then closed using wound clips and the mouse allowed to recover on a warming pad. Bladder wall injection is a delicate microsurgical technique that can be mastered with practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.