Evidence map›Paper›PMID 21775704›Full record

ArticleAmerican journal of physiology. Cell physiology2011

Leukocyte rolling and adhesion via ICAM-1 signals to endothelial permeability. Focus on "Leukocyte rolling and adhesion both contribute to regulation of microvascular permeability to albumin via ligation of ICAM-1".

Marcie R Williams, Francis W Luscinskas

Open access · greenAbstract readEditorialComment
In one paragraph

Article in American journal of physiology. Cell physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Induction of PD-1 and CD44 in CD4Journal of virology · 2025
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Endothelium-neutrophil interactions in ANCA-associated diseases.Journal of the American Society of Nephrology : JASN · 2012
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marcie R Williams
Francis W Luscinskas
Brigham and Women's Hospital · USHarvard University · US

Funding

VCAM-1 IN CHRONIC INFLAMMATORY AND IMMUNE PROCESSESP01HL036028 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MAYADAS, TANYA N · 1985 to 2013
$32.1M
MICROVASCULAR ENDOTHELIAL LYMPHOCYTE ADHESION UNDER FLOWR01HL053993 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LUSCINSKAS, FRANCIS W. · 1996 to 2009
$3.8M
Signaling Mechanisms in Leukocyte Transendothelial MigrationF32HL105016 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WILLIAMS, MARCIE R · 2010 to 2011
$99k
NHLBI NIH HHS F32 HL-105016NHLBI NIH HHS HL-053993NHLBI NIH HHS P0-1 HL-036028
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlbuminsAnimalsCapillary PermeabilityIntercellular Adhesion Molecule-1Leukocyte RollingLeukocytesAlbuminsIntercellular Adhesion Molecule-1

Identifiers

PMID21775704
PMCPMC3191568
OpenAlexW2069707499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.