Evidence map›Paper›PMID 21775584›Full record

ArticleThe Journal of general virology2011

Viruses in diarrhoeic dogs include novel kobuviruses and sapoviruses.

Linlin Li, Patricia A Pesavento, Tongling Shan, Christian M Leutenegger, Chunlin Wang, Eric Delwart

Open access · greenAbstract read
In one paragraph

Article in The Journal of general virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 145 citations in OpenAlex.

  1. Prevalence and Genomic Features of Aichivirus D in Yaks in Western China.Animals : an open access journal from MDPI · 2026
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  18. Molecular characterization of canine and feline kobuvirus infections in Iran.Veterinary research forum : an international quarterly journal · 2022
    Article
  19. Article
  20. Analysis of the gut microbiome in dogs and cats.Veterinary clinical pathology · 2022
    Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Linlin LiDepartment of Laboratory Medicine, University of California, San Francisco, CA, USA.
Patricia A PesaventoDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA.
Tongling ShanZoonosis and Comparative Medicine Group, Shanghai Jiao Tong University, Shanghai, Republic of China.
Christian M LeuteneggerIDEXX Laboratories, West Sacramento, CA, USA.
Chunlin WangStanford Genome Technology Center, Stanford, CA, USA.
Eric DelwartDepartment of Laboratory Medicine, University of California, San Francisco, CA, USA.
Blood Systems Research Institute · USIDEXX Laboratories (United States) · USNew York Genome Center · USShanghai Jiao Tong University · CNUniversity of California, Davis · USUniversity of California, San Francisco · US

Funding

Metagenomic analysis of the human viromeR01HL083254 · NHLBI · VITALANT · PI DELWART, ERIC L · 2007 to 2010
$1.6M
NHLBI NIH HHS R01 HL083254
6 · The paper itself

Abstract

The close interactions of dogs with humans and surrounding wildlife provide frequent opportunities for cross-species virus transmissions. In order to initiate an unbiased characterization of the eukaryotic viruses in the gut of dogs, this study used deep sequencing of partially purified viral capsid-protected nucleic acids from the faeces of 18 diarrhoeic dogs. Known canine parvoviruses, coronaviruses and rotaviruses were identified, and the genomes of the first reported canine kobuvirus and sapovirus were characterized. Canine kobuvirus, the first sequenced canine picornavirus and the closest genetic relative of the diarrhoea-causing human Aichi virus, was detected at high frequency in the faeces of both healthy and diarrhoeic dogs. Canine sapovirus constituted a novel genogroup within the genus Sapovirus, a group of viruses also associated with human and animal diarrhoea. These results highlight the high frequency of new virus detection possible even in extensively studied animal species using metagenomics approaches, and provide viral genomes for further disease-association studies.

Indexed as

AnimalsCaliciviridae InfectionsDiarrheaDog DiseasesDogsFecesHigh-Throughput Nucleotide SequencingKobuvirusMolecular Sequence DataPicornaviridae InfectionsSapovirusSequence Analysis, DNA

Identifiers

PMID21775584
PMCPMC3352364
OpenAlexW2122365084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.