ArticleGenetics2011
emb-1 encodes the APC16 subunit of the Caenorhabditis elegans anaphase-promoting complex.
Article in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Distinct D-box motifs in SPD-2 mediate APC/CFZR-1-dependent degradation and centrosomal localization in Caenorhabditis elegans embryos.G3 (Bethesda, Md.) · 2026Article
- Distinct D-box Motifs in SPD-2 Mediate APC/CbioRxiv : the preprint server for biology · 2025Article
- Correlations of expression of nuclear and mitochondrial genes in triploid fish.G3 (Bethesda, Md.) · 2022Article
- Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint.Cell reports · 2018Article
- APC/CG3 (Bethesda, Md.) · 2017Article
- Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome.Journal of molecular biology · 2015Article
- Article
- Control of oocyte growth and meiotic maturation in Caenorhabditis elegans.Advances in experimental medicine and biology · 2013Review
- Spermatogenesis.Advances in experimental medicine and biology · 2013Review
- SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is involved in early development and A-type cyclin stabilization.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In the nematode Caenorhabditis elegans, temperature-sensitive mutants of emb-1 arrest as one-cell embryos in metaphase of meiosis I in a manner that is indistinguishable from embryos that have been depleted of known subunits of the anaphase-promoting complex or cyclosome (APC/C). Here we show that the emb-1 phenotype is enhanced in double mutant combinations with known APC/C subunits and suppressed in double mutant combinations with known APC/C suppressors. In addition to its meiotic function, emb-1 is required for mitotic proliferation of the germline. These studies reveal that emb-1 encodes K10D2.4, a homolog of the small, recently discovered APC/C subunit, APC16.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.