ArticleJournal of virology2011
High prevalence of simian immunodeficiency virus infection in a community of savanna chimpanzees.
Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Local genetic adaptation to habitat in wild chimpanzees.Science (New York, N.Y.) · 2025Article
- Local genetic adaptation to habitat in wild chimpanzees.bioRxiv : the preprint server for biology · 2024Article
- Barriers to chimpanzee gene flow at the south-east edge of their distribution.Molecular ecology · 2023Article
- ZoonoticPathogens (Basel, Switzerland) · 2020Article
- The HLA A03 Supertype and SeveralJournal of virology · 2020Article
- CHIIMP: An automated high-throughput microsatellite genotyping platform reveals greater allelic diversity in wild chimpanzees.Ecology and evolution · 2018Article
- Ecology of sleeping: the microbial and arthropod associates of chimpanzee beds.Royal Society open science · 2018Article
- DNA recovery from wild chimpanzee tools.PloS one · 2018Article
- Destabilization of the gut microbiome marks the end-stage of simian immunodeficiency virus infection in wild chimpanzees.American journal of primatology · 2018Article
- The well-tempered SIV infection: Pathogenesis of SIV infection in natural hosts in the wild, with emphasis on virus transmission and early events post-infection that may contribute to protection from disease progression.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2016Article
- Why Are Nigeria-Cameroon Chimpanzees (Pan troglodytes ellioti) Free of SIVcpz Infection?PloS one · 2016Article
- Passive acoustic monitoring reveals group ranging and territory use: a case study of wild chimpanzees (Pan troglodytes).Frontiers in zoology · 2016Article
- High Rate of Simian Immunodeficiency Virus (SIV) Infections in Wild Chimpanzees in Northeastern Gabon.Viruses · 2015Article
- Barriers to, Efforts in, and Optimization of Integrated One Health Surveillance: A Review and Synthesis.EcoHealth · 2015Review
- Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas.mBio · 2015Article
- Sleeping site selection by savanna chimpanzees in Ugalla, Tanzania.Primates; journal of primatology · 2014Article
- African origin of the malaria parasite Plasmodium vivax.Nature communications · 2014Article
- Termite fishing by wild chimpanzees: new data from Ugalla, western Tanzania.Primates; journal of primatology · 2014Article
- Prevalence and climatic associated factors of Cryptosporidium sp. infections in savanna chimpanzees from Ugalla, Western Tanzania.Parasitology research · 2013Article
- The malagarasi river does not form an absolute barrier to chimpanzee movement in Western Tanzania.PloS one · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
Abstract
Simian immunodeficiency virus of chimpanzees (SIVcpz) has a significant negative impact on the health, reproduction, and life span of chimpanzees, yet the prevalence and distribution of this virus in wild-living populations are still only poorly understood. Here, we show that savanna chimpanzees, who live in ecologically marginal habitats at 10- to 50-fold lower population densities than forest chimpanzees, can be infected with SIVcpz at high prevalence rates. Fecal samples were collected from nonhabituated eastern chimpanzees (Pan troglodytes schweinfurthii) in the Issa Valley (n = 375) and Shangwa River (n = 6) areas of the Masito-Ugalla region in western Tanzania, genotyped to determine the number of sampled individuals, and tested for SIVcpz-specific antibodies and nucleic acids. None of 5 Shangwa River apes tested positive for SIVcpz; however, 21 of 67 Issa Valley chimpanzees were SIVcpz infected, indicating a prevalence rate of 31% (95% confidence interval, 21% to 44%). Two individuals became infected during the 14-month observation period, documenting continuing virus spread in this community. To characterize the newly identified SIVcpz strains, partial and full-length viral sequences were amplified from fecal RNA of 10 infected chimpanzees. Phylogenetic analyses showed that the Ugalla viruses formed a monophyletic lineage most closely related to viruses endemic in Gombe National Park, also located in Tanzania, indicating a connection between these now separated communities at some time in the past. These findings document that SIVcpz is more widespread in Tanzania than previously thought and that even very low-density chimpanzee populations can be infected with SIVcpz at high prevalence rates. Determining whether savanna chimpanzees, who face much more extreme environmental conditions than forest chimpanzees, are more susceptible to SIVcpz-associated morbidity and mortality will have important scientific and conservation implications.
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Registered trials
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