Evidence map›Paper›PMID 21774987›Full record

Trial reportGeneral hospital psychiatry

One-year postcollaborative depression care trial outcomes among predominantly Hispanic diabetes safety net patients.

Kathleen Ell, Wayne Katon, Bin Xie, Pey-Jiuan Lee, Suad Kapetanovic, Jeffrey Guterman, Chih-Ping Chou

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 15 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 15 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Effects of Multilevel and Multidomain Interventions on Glycemic Control in U.S. Hispanic Populations.International journal of environmental research and public health · 2025
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  15. Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kathleen EllSchool of Social Work, MRF 102R (MC 0411), University of Southern California, Los Angeles, CA 90089-0411, USA. ell@usc.edu
Wayne Katon
Bin Xie
Pey-Jiuan Lee
Suad Kapetanovic
Jeffrey Guterman
Chih-Ping Chou
University of Southern California · USClaremont Graduate University · USLos Angeles County Department of Health Services · USNational Institutes of Health · USUniversity of Washington · US

Funding

Psychiatry Consultation Liaison Service ResearchZIAMH002922 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PAO, MARYLAND · 2009 to 2025
$11.5M
Multifaceted Depression Diabetes Program for HispanicsR01MH068468 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ELL, KATHLEEN R · 2005 to 2008
$3.1M
NIMH NIH HHS R01 MH068468
6 · The paper itself

Abstract

objectiveThe aim of this study was to determine sustained effectiveness in reducing depression symptoms and improving depression care 1 year following intervention completion.

methodOf 387 low-income, predominantly Hispanic diabetes patients with major depression symptoms randomized to 12-month socioculturally adapted collaborative care (psychotherapy and/or antidepressants, telephone symptom monitoring/relapse prevention) or enhanced usual care, 264 patients completed 2-year follow-up. Depression symptoms (Symptom Checklist-20 [SCL-20], Patient Health Questionnaire-9 [PHQ-9]), treatment receipt, diabetes symptoms and quality of life were assessed 24 months postenrollment using intent-to-treat analyses.

resultsAt 24 months, more intervention patients received ongoing antidepressant treatment (38% vs. 25%, χ(2)=5.11, df=1, P=.02); sustained depression symptom improvement [SCL-20 <0.5 (adjusted odds ratio=2.06, 95% confidence interval=1.09-3.90, P=.03), SCL-20 score (adjusted mean difference -0.22, P=.001) and PHQ-9 ≥50% reduction (adjusted odds ratio=1.87, 95% confidence interval =1.05-3.32, P=.03)]. Over 2 years, improved effects were found in significant study group by time interaction for Short Form-12 mental health, Sheehan Disability Scale (SDS) functional impairment, diabetes symptoms, anxiety and socioeconomic stressors (P=.02 for SDS; P<.0001 for all others); however, group differences narrowed over time and were no longer significant at 24 months.

conclusionsSocioculturally tailored collaborative care that included maintenance antidepressant medication, ongoing symptom monitoring and behavioral activation relapse prevention was associated with depression improvement over 24 months for predominantly Hispanic patients in primary safety net care.

Indexed as

AdultAgedAntidepressive AgentsCooperative BehaviorCultural CharacteristicsDiabetes MellitusFemaleHealth Services AccessibilityHispanic or LatinoHumansIntention to Treat AnalysisInterdisciplinary CommunicationMajor Depressive DisorderMaleMiddle AgedPatient SatisfactionAntidepressive Agents

Identifiers

PMID21774987
PMCPMC3175272
OpenAlexW2077141434

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.