Evidence map›Paper›PMID 21772975›Full record

ArticleJournal of osteoporosis2011

A randomized controlled trial of whole body vibration exposure on markers of bone turnover in postmenopausal women.

Sarah Turner, Margaret Torode, Mike Climstein, Geraldine Naughton, David Greene, Michael K Baker, Maria A Fiatarone Singh

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of osteoporosis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03560154 (Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease), which is not on this map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03560154 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease: A Randomized Controlled Trial

TypeinterventionalSponsorIstanbul UniversityRan2017 to 2020Enrolled60ConditionsInterstitial Lung Disease, Scleroderma, Idiopathic Pulmonary FibrosisArmsWhole Body Vibration Training
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  17. Acute bone response to whole body vibration in healthy pre-pubertal boys.Journal of musculoskeletal & neuronal interactions · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah TurnerExercise, Health and Performance Faculty Research Group, Faculty of Health Sciences, The University of Sydney, Lidcombe, NSW 1825, Australia.
Margaret Torode
Mike Climstein
Geraldine Naughton
David Greene
Michael K Baker
Maria A Fiatarone Singh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose. To examine the effects of two doses of low-frequency (12 Hz), low-magnitude (0.3 g), whole body vibration on markers of bone formation and resorption in postmenopausal women. Methods. Women were recruited and randomized into a sham vibration control group, one time per week vibration group (1×/week), or three times per week vibration group (3×/week). Vibration exposure consisted of 20 minutes of intermittent vibration for the 1×/week and 3×/week groups, and sham vibration (<0.1 g) for the control group for eight weeks. Double-blinded primary outcome measures were urine markers of bone resorption: N-telopeptide X normalised to creatinine (NTx/Cr) and bone formation: bone-specific alkaline phosphatase (ALP). Results. Forty-six women (59.8 ± 6.2 years, median 7.3 years since menopause) were enrolled. NTx/Cr was significantly reduced (34.6%) in the 3×/wk vibration group but not in the 1×/wk vibration group compared with sham control (P < .01) group. No effect of time or group allocation was observed on the bone formation marker ALP (P = .27). Conclusion. We have shown for the first time that low-frequency, low-magnitude vibration 3×/week for eight weeks in postmenopausal women results in a significant reduction in NTx/Cr, a marker of bone resorption, when compared with sham vibration exposure.

Identifiers

PMID21772975
PMCPMC3135216

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.