ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2009
Associates of poor physical and mental health-related quality of life in beta thalassemia-major/intermedia.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Health-related quality of life in hemoglobinopathies: A systematic review from a global perspective.Frontiers in pediatrics · 2022Pooled it
- Health-related quality of life (HRQoL) in beta-thalassemia major (β-TM) patients assessed by 36-item short form health survey (SF-36): a meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Pooled it
- Association between health-related quality of life and medication discrepancies: a cross-sectional study of older Chinese adults with type 2 diabetes mellitus.Health and quality of life outcomes · 2026Article
- Effectiveness of educational intervention on quality of life in adults with thalassemia major: A quasi-experimental study based on PRECEDE model.Health science reports · 2024Article
- Awareness and practical evaluation of correct use of iron chelators; a study to track the ambiguities of thalassemia patients on their medications in Iran.BMC research notes · 2024Article
- Gender Disparities in Psychological Disturbances and Quality of Life Among Adolescent and Adult Patients with Thalassemia: A Review.Journal of multidisciplinary healthcare · 2024Review
- Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire.Scientific reports · 2023Article
- Article
- Medical student acceptance on gene therapy to increase children's well-being with genetic diseases: a study in Indonesia.Future science OA · 2022Article
- Quality of Life and Related Paraclinical Factors in Iranian Patients with Transfusion-Dependent Thalassemia.Journal of environmental and public health · 2021Article
- Prevalence of Transfusion Transmitted Infections and the Quality of Life in β-thalassemia Major Patients.Cureus · 2019Article
- Anxiety and depression in patients with gastroesophageal reflux disorder.Electronic physician · 2017Article
- Failure to replicate the internal structure of Greek-specific thalassemia quality of life instrument in adult thalassemia patients in Sabah.Patient preference and adherence · 2016Article
- Associations between a health-promoting lifestyle and quality of life among adults with beta-thalassemia major.Epidemiology and health · 2016Article
- Comparison of Blood Transfusion Plus Chelation Therapy and Bone Marrow Transplantation in Patients with β-Thalassemia: Application of SF-36, EQ-5D, and Visual Analogue Scale Measures.International journal of health policy and management · 2015Article
- Does Multi-morbidity Mediate the Effect of Socioeconomics on Self-rated Health? Cross-country Differences.International journal of preventive medicine · 2015Article
- Association between number of comorbid medical conditions and depression among individuals with diabetes; race and ethnic variations.Journal of diabetes and metabolic disorders · 2015Article
- Cross-Country Differences in the Additive Effects of Socioeconomics, Health Behaviors and Medical Comorbidities on Disability among Older Adults with Heart Disease.The journal of Tehran Heart Center · 2015Article
- Depression Mediates the Effect of Sexual Function on Quality of Life among Men but Not Women with Coronary Artery Disease.International cardiovascular research journal · 2014Article
- Cross-country variation in additive effects of socio-economics, health behaviors, and comorbidities on subjective health of patients with diabetes.Journal of diabetes and metabolic disorders · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUsing two logistic regression models, we determined the associates of poor physical and mental health related quality of life (HRQoL) among beta thalassemia patients.
methodsIn this cross-sectional study which was conducted during 2006 and 2007 in outpatient adult thalassemia clinic, Blood Transfusion Organization, Tehran, Iran, Short Form 36 (SF-36) was used for measuring HRQoL in 179 patients with beta thalassemia (major/intermedia). We determined scores higher than third quartiles of obtained PCS and MCS scores as the cutoff points of good HRQoL. Poor HRQoL was defined scores lower than first quartiles of obtained PCS and MCS scores. Two distinct logistic regression models were used to derive associated variables including demographic, clinical, and psychological factors.
resultsThe regression models suggested that poor physical HRQoL was positively associated with somatic comorbidities (OR = 1.472, CI = 1.021-2.197, p = 0.048) and depression score (OR = 8.568, CI = 2.325-31.573, p = 0.001). The variables that were associated with poor mental HRQoL were anxiety score (OR = 9.409, CI = 1.022-89.194, p = 0.049) and depression score (OR = 20.813, CI = 4.320-100.266, p < 0.001).
conclusionsDepression is associated with both poor physical and mental HRQoL among patients with major/intermedia beta thalassemia, however somatic comorbidities and anxiety are associated with poor physical and mental HRQoL, respectively.
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Identifiers
21772908PMC3129078What OpenQuestion holds
Registered trials
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