Evidence map›Paper›PMID 21772834›Full record

ArticleFrontiers in microbiology2011

Interactions of bacterial proteins with host eukaryotic ubiquitin pathways.

Charlotte Averil Perrett, David Yin-Wei Lin, Daoguo Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Secretory microRNA Profiles of Third- and Fourth-StagePathogens (Basel, Switzerland) · 2021
    Article
  3. Article
  4. Article
  5. Review
  6. The ubiquitin ligase SspH1 fromThe Journal of biological chemistry · 2019
    Article
  7. Frontiers in immunology · 2019
    Article
  8. Article
  9. Review
  10. Article
  11. How Do the Virulence Factors ofFrontiers in cellular and infection microbiology · 2017
    Review
  12. Review
  13. Review
  14. Article
  15. Assembly, analysis and architecture of atypical ubiquitin chains.Nature structural & molecular biology · 2013
    Article
  16. Article
  17. Epigenetics and bacterial infections.Cold Spring Harbor perspectives in medicine · 2012
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Charlotte Averil PerrettDepartment of Biological Sciences, Purdue University West Lafayette, IN, USA.
David Yin-Wei Lin
Daoguo Zhou
State Street (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ubiquitination is a post-translational modification in which one or more 76 amino acid polypeptide ubiquitin molecules are covalently linked to the lysine residues of target proteins. Ubiquitination is the main pathway for protein degradation that governs a variety of eukaryotic cellular processes, including the cell-cycle, vesicle trafficking, antigen presentation, and signal transduction. Not surprisingly, aberrations in the system have been implicated in the pathogenesis of many diseases including inflammatory and neurodegenerative disorders. Recent studies have revealed that viruses and bacterial pathogens exploit the host ubiquitination pathways to gain entry and to aid their survival/replication inside host cells. This review will summarize recent developments in understanding the biochemical and structural mechanisms utilized by bacterial pathogens to interact with the host ubiquitination pathways.

Indexed as

bacterial pathogenDUBE3 ligaseF-boxubiquitin

Identifiers

PMID21772834
PMCPMC3131157
OpenAlexW2038923492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.