ArticleDevelopmental biology2011
NudC is required for interkinetic nuclear migration and neuronal migration during neocortical development.
Article in Developmental biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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Who cites it
27 citing papers in PubMed, 43 citations in OpenAlex.
- PSME3 regulates migration and differentiation of myoblasts.Life science alliance · 2025Article
- Early spinal cord development: from neural tube formation to neurogenesis.Nature reviews. Neuroscience · 2025Review
- NUDC Is Critical for Mitosis and Postmitotic Cell Maintenance Through Its Modulation of Dynein and Actin Cytoskeletal Reorganization.Advances in experimental medicine and biology · 2025Review
- Quantitative in toto live imaging analysis of apical nuclear migration in the mouse telencephalic neuroepithelium.Development, growth & differentiation · 2024Article
- NUDC is critical for rod photoreceptor function, maintenance, and survival.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Radial glia progenitor polarity in health and disease.Frontiers in cell and developmental biology · 2024Review
- Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.International journal of molecular sciences · 2023Article
- NudC regulated Lis1 stability is essential for the maintenance of dynamic microtubule ends in axon terminals.iScience · 2022Article
- Article
- Cataloguing and Selection of mRNAs Localized to Dendrites in Neurons and Regulated by RNA-Binding Proteins in RNA Granules.Biomolecules · 2020Review
- NudC regulates photoreceptor disk morphogenesis and rhodopsin localization.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019Article
- AnToxicology research · 2016Article
- Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages.Nature communications · 2016Article
- Decoding the molecular mechanisms of neuronal migration using in utero electroporation.Medical molecular morphology · 2016Review
- Dynamic Phosphorylation of NudC by Aurora B in Cytokinesis.PloS one · 2016Article
- EML4 promotes the loading of NUDC to the spindle for mitotic progression.Cell cycle (Georgetown, Tex.) · 2015Article
- Morphological and functional aspects of progenitors perturbed in cortical malformations.Frontiers in cellular neuroscience · 2015Review
- miR-139-5p modulates cortical neuronal migration by targeting Lis1 in a rat model of focal cortical dysplasia.International journal of molecular medicine · 2014Article
- Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.Molecular biology of the cell · 2014Article
- The microcephaly protein Asp regulates neuroepithelium morphogenesis by controlling the spatial distribution of myosin II.Nature cell biology · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
NudC is a highly conserved protein necessary for cytoplasmic dynein-mediated nuclear migration in Aspergillus nidulans. NudC interacts genetically with Aspergillus NudF and physically with its mammalian orthologue Lis1, which is crucial for nuclear and neuronal migration during brain development. To test for related roles for NudC, we performed in utero electroporation into embryonic rat brain of cDNAs encoding shRNAs as well as wild-type and mutant forms of NudC. We show here that NudC, like Lis1, is required for neuronal migration during neocorticogenesis and we identify a specific role in apical nuclear migration in radial glial progenitor cells. These results identify a novel neuronal migration gene with a specific role in interkinetic nuclear migration, consistent with cytoplasmic dynein regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.