Evidence map›Paper›PMID 21770763›Full record

ArticleAIDS patient care and STDs2011

Quality of sleep: associations with antiretroviral nonadherence.

Parya Saberi, Torsten B Neilands, Mallory O Johnson

Abstract read
In one paragraph

Article in AIDS patient care and STDs, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Assessing sleep using the Pittsburgh Sleep Quality Index (PSQI) among comorbid HIV and psychiatric outpatients.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
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  15. Metabolomics of sleep disorders in HIV: a narrative review.Sleep & breathing = Schlaf & Atmung · 2020
    Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Parya SaberiCenter for AIDS Prevention Studies, University of California San Francisco, USA. parya.saberi@ucsf.edu
Torsten B Neilands
Mallory O Johnson
University of California, San Francisco · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057616 · NIMH · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MORIN, STEPHEN F · 2001 to 2004
$2.9M
Dyadic Processes in the Patient-Provider RelationshipK24MH087220 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2009 to 2013
$771k
Quality of Sleep in HIV-Infection: associations with treatment and adherenceF32MH086323 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SABERI, PARYA · 2009 to 2011
$193k
NIAID NIH HHS P30 AI027763NIMH NIH HHS F32 MH086323NIMH NIH HHS F32MH086323NIMH NIH HHS K24 MH087220NIMH NIH HHS K24MH087220NIMH NIH HHS P30 MH62246NIMH NIH HHS U10MH057616
6 · The paper itself

Abstract

Poor quality of sleep (QOS) is frequently reported in HIV-positive individuals; however, despite its clinical and public health significance, few studies have examined the correlation between QOS and antiretroviral (ARV) adherence. The objective of this study was to estimate the prevalence of sleep disturbances, determine the characteristics of those with poor QOS, and establish the relationship between QOS and ARV nonadherence among HIV-positive individuals. We conducted a cross-sectional secondary data analysis of 2845 HIV-positive adults taking ARV therapy from the Healthy Living Project baseline cohort. Mean self-reported ARV nonadherence was estimated using a 3-day measure. QOS was assessed using three questions regarding sleep pattern changes, amount of bother from difficulty falling/staying asleep, and amount of bother from vivid dreams. Over 68% of individuals reported sleep pattern changes, 50.3% reported difficulty falling/staying asleep, and 20.5% reported bother from vivid dreams. Depression, suicidal ideation, unemployment, use of illicit substances, history of incarceration, and HIV viral load were all independently associated with poor QOS. Individuals reporting feeling bothered about difficulty falling/staying asleep had a 1.66 higher odds of nonadherence (95% confidence interval [CI]=1.18, 2.33; p=0.004). Those reporting the highest degree of bother from difficulty falling/staying asleep and from vivid dreams had a 1.42 (95% CI=1.13, 1.78; p=0.002) and 1.31 (95% CI=0.98, 1.75; p=0.07) higher odds of nonadherence, respectively. With higher incremental reports of poor QOS there were considerable increases in ARV nonadherence. Recognition and timely treatment of sleep difficulties may result in reduced ARV nonadherence with beneficial clinical and public health implications.

Indexed as

Patient ComplianceAnti-HIV AgentsCohort StudiesCross-Sectional StudiesFemaleHIV InfectionsHumansMaleOdds RatioRisk FactorsSleep Wake DisordersViral LoadAnti-HIV Agents

Identifiers

PMID21770763
PMCPMC3157301
OpenAlexW2064981489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.