Trial reportBirth defects research. Part A, Clinical and molecular teratology2011
A description of congenital anomalies among infants in Entebbe, Uganda.
Trial report in Birth defects research. Part A, Clinical and molecular teratology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Birth prevalence of neural tube defects in eastern Africa: a systematic review and meta-analysis.BMC neurology · 2022Pooled it
- Proportion of Chromosomal Disorders and Their Patterns among Births with Congenital Anomalies in Africa: A Systematic Review and Meta-Analyses.TheScientificWorldJournal · 2022Pooled it
- Prevalence and associated factors of birth defects among newborns in sub-Saharan African countries: a systematic review and meta-analysis.The Pan African medical journal · 2020Pooled it
- The safety of atovaquone-proguanil for the prevention and treatment of malaria in pregnancy: A systematic review.Travel medicine and infectious diseasePooled it
- Cohort profile: the Entebbe Mother and Baby Study (EMaBS).BMJ open · 2026Trial
- Trial
- Pregnancy outcome documentation in low-resource settings: a multi-country study.AJOG global reports · 2026Article
- Patterns and risk factors of birth defects in Bangladesh: evidence from a neonatal intensive care unit.BMC pregnancy and childbirth · 2026Observational
- Persistent umbilical discharge beyond the neonatal period due to patent urachus in an infant managed in a resource-limited setting: a case report.International journal of surgery case reports · 2026Article
- Proportion, factors hindering, and experiences regarding cardiac screening in children with Down syndrome at Mulago National Referral Hospital: a cross-sectional multimethod study.BMC pediatrics · 2026Article
- Developing and validating a neonatal screening tool for congenital anomalies to be used in low- and middle-income country settings.BMJ global health · 2026Article
- Registries and surveillance models used to screen neonates for congenital anomalies in LMIC settings: a scoping review.BMJ public health · 2026Article
- Low Birth Weight Newborns at Public Hospitals in the Awi Zone of Northwest Ethiopia: Birth Defects and Associated Variables.International journal of pediatrics · 2026Article
- A retrospective study of congenital anomalies and associated risk factors among children admitted at a tertiary hospital in northwestern Tanzania.PLOS global public health · 2024Article
- Adherence to iron and folate supplementation and associated factors among women attending antenatal care in public health facilities at Covid-19 pandemic in Ethiopia.PLOS global public health · 2023Article
- Congenital anomalies during the 2015-2018 Zika virus epidemic: a population-based cross-sectional study.BMC public health · 2022Article
- Prevalence of neural tube defects, maternal HIV status, and antiretroviral therapy from a hospital-based birth defect surveillance in Kampala, Uganda.Birth defects research · 2022Article
- Incidence and Associated Factors of Major Congenital Anomalies in Newborns in Chaharmahal and Bakhtiari, Southwest of Iran.International journal of preventive medicine · 2022Article
- Trends of Hospital Admissions Due to Congenital Anomalies in England and Wales between 1999 and 2019: An Ecological Study.International journal of environmental research and public health · 2021Article
- Congenital anomalies among newborn babies in Felege-Hiwot Comprehensive Specialized Referral Hospital, Bahir Dar, Ethiopia.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundData on congenital anomalies from developing countries of the sub-Saharan region are scarce. However, it is important to have comprehensive and reliable data on the description and prevalence of congenital anomalies to allow surveillance and the implementation of appropriate public health strategies for prevention and management. In this study, we describe the profile of congenital anomalies seen in a birth cohort in Entebbe, Uganda.
methodsCongenital anomalies were defined as any structural defect present at birth. Pregnant women were recruited to the cohort between 2003 and 2005. Defects present at birth were recorded by the midwife at delivery and by physicians at the routine six-week postnatal visit and at illness-related visits until 1 year of life. The anomalies were classified by organ system according to the 10th version of the World Health Organization International Classification of Diseases (ICD-10).
resultsThere were 180 infants with a congenital anomaly among 2365 births. The most commonly affected systems were the musculoskeletal (42.7 per 1000 births) and skin (16.1 per 1000 births). The prevalence of major anomalies was 20.3 per 1000 births; 1.7 per 1000 births for cardiac anomalies and 1.3 per 1000 births for neural system anomalies. Forty (22%) of the congenital anomalies were identified at birth, 131 (73%) at the 6-week postnatal visit, and nine (5%) at illness-related visits.
conclusionCongenital anomalies are common in developing countries. Establishment of comprehensive databases for surveillance would be helpful for surveillance of effects of new exposures, for prevention, management, and health care planning.
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