Evidence map›Paper›PMID 21769665›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2012

Non-contrast magnetic resonance imaging for guiding left ventricular lead position in cardiac resynchronization therapy.

Mads Brix Kronborg, Won Yong Kim, Peter Thomas Mortensen, Jens Cosedis Nielsen

Abstract read
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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Determinants of Response to Cardiac Resynchronization Therapy.The Journal of innovations in cardiac rhythm management · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Nuclear image-guided left ventricular pacing lead navigation feasibility of a new technique.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2015
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mads Brix KronborgDepartment of Cardiology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, 8200, Aarhus N, Denmark. mads.brix.kronborg@ki.au.dk
Won Yong Kim
Peter Thomas Mortensen
Jens Cosedis Nielsen
Aarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA left ventricular lead position concordant to viable myocardium at the site of latest mechanical activation is associated with a better response to cardiac resynchronization therapy (CRT). The present study aimed to guide left ventricular (LV) lead implantation into a vein over the area of latest mechanical activation with no transmural scar as determined by radial strain measured by non-contrast magnetic resonance imaging (MRI).

methodsPatients admitted for CRT implantation underwent MRI on the day before pacemaker implantation. Time to peak radial strain in ventricular segments was measured to define the site of latest mechanical activation. Areas with peak radial strain less than 16.5% were defined as transmural scar. Venograms were visualized to define the optimal vein for LV lead positioning. Echocardiograms, 6-min hall walk test, and NYHA class were obtained at baseline and after 6 months of follow-up.

resultsSixteen patients were included. In nine patients the lead was positioned at the primary target site, and in six patients a secondary was used owing to phrenic nerve stimulation (one patient), unstable lead position (two patients) and lack of suitable vein (three patients) at the primary target site. In three patients pre-implant MRI changed the implanters primary target vein.

conclusionNon-contrast MRI can be used to detect the site of latest mechanical activation by radial strain to guide LV lead positioning in candidates for CRT. Image guided LV lead implantation in CRT patients may in some patients change the primary target tributary of the coronary sinus.

Indexed as

Cardiac Resynchronization TherapyHeart VentriclesMagnetic Resonance Imaging, InterventionalAgedAged, 80 and overContrast MediaEchocardiographyElectrodes, ImplantedFemaleHumansMaleMiddle AgedMyocardial IschemiaContrast Media

Identifiers

PMID21769665
OpenAlexW2026117627

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.