Evidence map›Paper›PMID 21769316›Full record

ArticleRare tumors2011

Three cases of bone metastases in patients with gastrointestinal stromal tumors.

Valerio Di Scioscio, Laura Greco, Maria Caterina Pallotti, Maria Abbondanza Pantaleo, Alessandra Maleddu, Margherita Nannini, Alberto Bazzocchi, Monica Di Battista, Anna Mandrioli, Cristian Lolli and 4 more

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In one paragraph

Article in Rare tumors, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Valerio Di ScioscioDepartment of Radiology, Sant'Orsola Malpighi Hospital, Bologna University, Bologna, Italy.
Laura Greco
Maria Caterina Pallotti
Maria Abbondanza Pantaleo
Alessandra Maleddu
Margherita Nannini
Alberto Bazzocchi
Monica Di Battista
Anna Mandrioli
Cristian Lolli
Maristella Saponara
Garzillo Giorgio
Guido Biasco
Maurizio Zompatori
Policlinico S.Orsola-Malpighi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal stromal tumors (GISTs) are rare, but represent the most common mesenchymal neoplasms of the gastrointestinal tract. Tumor resection is the treatment of choice for localized disease. Tyrosine kinase inhibitors (imatinib, sunitinib) are the standard therapy for metastatic or unresectable GISTs. GISTs usually metastasize to the liver and peritoneum. Bone metastases are uncommon. We describe three cases of bone metastases in patients with advanced GISTs: two women (82 and 54 years of age), and one man (62 years of age). Bones metastases involved the spine, pelvis and ribs in one patient, multiple vertebral bodies and pelvis in one, and the spine and iliac wings in the third case. The lesions presented a lytic pattern in all cases. Two patients presented with multiple bone metastases at the time of initial diagnosis and one patient after seven years during the follow-up period. This report describes the diagnosis and treatment of the lesions and may help clinicians to manage bones metastases in GIST patients.

Indexed as

bone metastasescomputerezed tomografygastrointestinal stromal tumorsImatinib.scan

Identifiers

PMID21769316
PMCPMC3132121
OpenAlexW1974060642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.