ArticleNature chemical biology2011
Chronicles of the GTPase switch.
Article in Nature chemical biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer.Cell reports. Medicine · 2025Article
- Somatic RAP1B gain-of-function variant underlies isolated thrombocytopenia and immunodeficiency.The Journal of clinical investigation · 2024Article
- Exploring Covalent Bond Formation at Tyr-82 for Inhibition of Ral GTPase Activation.ChemMedChem · 2023Article
- AMPylation of small GTPases by Fic enzymes.FEBS letters · 2023Review
- AtypicalScience advances · 2022Article
- Covalent Fragment Screening Identifies Rgl2 RalGEF Cysteine for Targeted Covalent Inhibition of Ral GTPase Activation.ChemMedChem · 2022Article
- RHO GTPases: from new partners to complex immune syndromes.Nature reviews. Immunology · 2021Review
- The Game of Tubulins.Cells · 2021Review
- Structural Design and Analysis of the RHOA-ARHGEF1 Binding Mode: Challenges and Applications for Protein-Protein Interface Prediction.Frontiers in molecular biosciences · 2021Article
- Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.Nature communications · 2019Article
- Article
- PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.Nature chemical biology · 2019Article
- Molecular mechanism of ATP versus GTP selectivity of adenylate kinase.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Intracellular mature IL-37 suppresses tumor metastasis via inhibiting Rac1 activation.Oncogene · 2018Article
- The type IV pilus assembly ATPase PilB functions as a signaling protein to regulate exopolysaccharide production in Myxococcus xanthus.Scientific reports · 2017Article
- Thermodynamic Bounds on the Ultra- and Infra-affinity of Hsp70 for Its Substrates.Biophysical journal · 2017Article
- Identification of a Fragmented Small GTPase Capable of Conditional Effector Binding.RSC advances · 2017Article
- Paradoxical signaling regulates structural plasticity in dendritic spines.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
21769091What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.