Evidence map›Paper›PMID 21768607›Full record

ReviewCold Spring Harbor perspectives in biology2011

RNA granules in germ cells.

Ekaterina Voronina, Geraldine Seydoux, Paolo Sassone-Corsi, Ippei Nagamori

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 209 papers.

0numbers the graph read from it
0cells of the map it votes in
209citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

209 citing papers in PubMed, 382 citations in OpenAlex.

  1. Article
  2. Sex Determination in Sponges.Molecular reproduction and development · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. eIF4E assembly intobioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Abundant piRNA production mediated by theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article

149 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ekaterina VoroninaDepartment of Molecular Biology and Genetics and Howard Hughes Medical Institute, Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. evoronina@jhmi.edu
Geraldine Seydoux
Paolo Sassone-Corsi
Ippei Nagamori
Howard Hughes Medical Institute · USUniversity of California, Irvine · US

Funding

REGULATION OF GERM CELL FATE DURING EMBRYOGENESISR01HD037047 · NICHD · JOHNS HOPKINS UNIVERSITY · PI GERALDINE Catherine Joelle SEYDOUX · 1999 to 2026
$4.3M
Regulation of Germ Cell Fate During EmbryogenesisR37HD037047 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SEYDOUX, GERALDINE CATHERINE JOELLE · 2016 to 2025
$3.8M
Chromatin Remodeling and Circadian Clock ControlR01GM081634 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SASSONE-CORSI, PAOLO · 2007 to 2011
$1.6M
Components of C. elegans P-granules and regulation of their functionF32GM080923 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VORONINA, EKATERINA · 2007 to 2009
$165k
Howard Hughes Medical InstituteNICHD NIH HHS HD37047NICHD NIH HHS R01 HD037047NICHD NIH HHS R37 HD037047NIGMS NIH HHS 5F32GM080923NIGMS NIH HHS F32 GM080923NIGMS NIH HHS GM081634NIGMS NIH HHS R01 GM081634
6 · The paper itself

Abstract

"Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and function. One hypothesis is that germ granules operate as hubs for the posttranscriptional control of gene expression, a function at the core of the germ cell differentiation program.

Indexed as

AnimalsCaenorhabditis elegansCell DifferentiationChromatinCytoplasmic GranulesDrosophilaGerm CellsMitosisProtein Structure, TertiaryRNARNA StabilityChromatinRNA

Identifiers

PMID21768607
PMCPMC3225947
OpenAlexW2162396952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.