Evidence map›Paper›PMID 21768510›Full record

ArticleAntimicrobial agents and chemotherapy2011

New transposon Tn6133 in methicillin-resistant Staphylococcus aureus ST398 contains vga(E), a novel streptogramin A, pleuromutilin, and lincosamide resistance gene.

Sybille Schwendener, Vincent Perreten

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Genomic comparison of methicillin-resistantFrontiers in microbiology · 2026
    Article
  2. Characterisation ofToxins · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Whole genome sequence-based analysis ofFrontiers in microbiology · 2023
    Article
  8. Vancomycin Resistance inMicroorganisms · 2022
    Review
  9. Molecular Mechanisms of Drug Resistance inInternational journal of molecular sciences · 2022
    Review
  10. Genetic characterization of livestock-associated methicillin-resistant Staphylococcus aureus isolated in Greece.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  11. Article
  12. Article
  13. A Conjugative MDR pMG1-Like Plasmid Carrying theFrontiers in microbiology · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. TnAntimicrobial agents and chemotherapy · 2019
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sybille SchwendenerInstitute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Länggass-Strasse 122, CH-3012 Bern, Switzerland.
Vincent Perreten

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel streptogramin A, pleuromutilin, and lincosamide resistance determinant, Vga(E), was identified in porcine methicillin-resistant Staphylococcus aureus (MRSA) ST398. The vga(E) gene encoded a 524-amino-acid protein belonging to the ABC transporter family. It was found on a multidrug resistance-conferring transposon, Tn6133, which was comprised of Tn554 with a stably integrated 4,787-bp DNA sequence harboring vga(E). Detection of Tn6133 in several porcine MRSA ST398 isolates and its ability to circularize suggest a potential for dissemination.

Indexed as

DNA Transposable ElementsAnimalsAnti-Bacterial AgentsATP-Binding Cassette TransportersBacterial ProteinsBase SequenceDiterpenesDrug Resistance, Multiple, BacterialGenes, BacterialLincosamidesMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMolecular Sequence DataPlasmidsPleuromutilinsPolycyclic CompoundsAnti-Bacterial AgentsATP-Binding Cassette TransportersBacterial ProteinsDiterpenesDNA Transposable ElementsLincosamidesPleuromutilinsPolycyclic CompoundsStreptogramin AVgA protein, Staphylococcus aureus

Identifiers

PMID21768510
PMCPMC3187003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.