Trial reportPediatrics2011
Evidence for catch-up in cognition and receptive vocabulary among adolescents born very preterm.
Trial report in Pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00033917 (Randomized Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage), which is not on this map. Cited by 52 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial
Who cites it
52 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Social-environmental moderators of neurodevelopmental outcomes in youth born preterm: A systematic review.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2021Pooled it
- Predicting the outcomes of preterm neonates beyond the neonatal intensive care unit: What are we missing?Pediatric research · 2021Pooled it
- A gradient relationship between low birth weight and IQ: A meta-analysis.Scientific reports · 2017Pooled it
- Trial
- Tackling Acquisition of Language in Kids born Preterm (TALK-Preterm): protocol of a prospective cohort study.Research square · 2026Article
- Executive function and implications for the Preterm Behavioral Phenotype in very preterm children at age 9-10 years.Journal of neurodevelopmental disorders · 2026Article
- Translating the Power of Precision Medicine Into the World of Communication Disorders.Journal of speech, language, and hearing research : JSLHR · 2025Review
- The transfusion of prematures early school age follow-up (TOP 5): protocol for a longitudinal cohort study.BMC pediatrics · 2025Article
- Cognitive, language and motor developmental patterns of extremely preterm children up to 2 years of age: a descriptive approach.Frontiers in psychology · 2025Article
- Characterization of language abilities and semantic networks in very preterm children at school-age.PloS one · 2025Article
- A Comparative Analysis of Language Skills and Parent-Child Interactions in Monolingual and Bilingual Children Born Preterm.Languages (Basel, Switzerland) · 2024Article
- The impact of premature birth on auditory-visual processes in very preterm schoolchildren.NPJ science of learning · 2024Article
- Home Musical Activities Boost Premature Infants' Language Development.Children (Basel, Switzerland) · 2024Article
- Structural connectivity at term equivalent age and language in preterm children at 2 years corrected.Brain communications · 2024Article
- Prenatal experience with language shapes the brain.Science advances · 2023Article
- Language Impairment in Children of Mothers with Gestational Diabetes, Preeclampsia, and Preterm Delivery: Current Hypothesis and Potential Underlying Mechanisms : Language Impartment and Pregnancy Complications.Advances in experimental medicine and biology · 2023Article
- Latent class growth analysis identified different trajectories in cognitive development of extremely low birthweight children.BMJ paediatrics open · 2022Article
- Functional Hyperconnectivity during a Stories Listening Task in Magnetoencephalography Is Associated with Language Gains for Children Born Extremely Preterm.Brain sciences · 2021Article
- Children Born Prematurely May Demonstrate Catch-Up Growth in Pre-Adolescence.Language, speech, and hearing services in schools · 2021Article
- Stability of Executive Functioning of Moderately-Late Preterm and Full-Term Born Children at Ages 11 and 19: The TRAILS Cohort Study.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundVery preterm adolescents display persistent deficits in neuropsychological functions.
objectiveTo compare cognitive and language outcomes at 16 years and cognitive and receptive vocabulary trajectories throughout school years between very preterm and term children and to determine child and family factors associated with better developmental trajectories. DESIGN AND
methodsAt 8, 12, and 16 years, 322 very preterm children with birth weights of 1250 g or less and 41 term children had cognitive and language testing. Hierarchical growth-curve modeling was used to delineate the differences in cognitive and receptive vocabulary development between participants. Cluster analyses allowed for the characterization of very preterm children with different patterns of cognitive and receptive vocabulary development.
resultsAt 16 years, very preterm adolescents had deficits in general cognition and higher-order language skills (phonological awareness and phonemic decoding) compared with term peers. Although the between-group difference in cognitive scores remained stable from 8 to 16 years, very preterm children demonstrated catch-up gains in receptive vocabulary during the same period. Moreover, subgroups of very preterm children displayed developmental trajectories in cognition similar to term children (55% on the vocabulary and 46% on the block-design subtests). These children had lower rates of neurosensory impairment and mothers with higher education and were from an ethnic nonminority.
conclusionsSignificant catch-up in receptive vocabulary is observed by the age of 16 years among very preterm children compared to term peers. The absence of neurosensory impairment and residing in a favorable socioeconomic milieu are associated with the most optimal developmental trajectories.
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