ArticleBiophysical journal2011
Electrodynamics of lipid membrane interactions in the presence of zwitterionic buffers.
Article in Biophysical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- ICSI media buffers: is there room for improvement?Journal of assisted reproduction and genetics · 2026Review
- Bicarbonate buffer enhances functional sperm selection compared to Zwitterionic buffers in sperm preparation.Scientific reports · 2026Article
- Exploring wide gap semiconductor characteristics inJournal of molecular modeling · 2024Article
- Influx of zwitterionic buffer after intracytoplasmic sperm injection (ICSI) membrane piercing alters the transcriptome of human oocytes.Journal of assisted reproduction and genetics · 2024Article
- SEDNTERP: a calculation and database utility to aid interpretation of analytical ultracentrifugation and light scattering data.European biophysics journal : EBJ · 2023Article
- On the structural, electronic, and optical properties of L-histidine crystal: a DFT study.Journal of molecular modeling · 2023Article
- Location of dopamine in lipid bilayers and its relevance to neuromodulator function.Biophysical journal · 2023Article
- Divergent Synthesis of Ultrabright and Dendritic Xanthenes for Enhanced Click-Chemistry-Based Bioimaging.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Anti-F1000Research · 2020Article
- Identification of Specific Lysines and Arginines That Mediate Angiomotin Membrane Association.ACS omega · 2019Article
- Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin.The journal of physical chemistry. B · 2018Article
- A simple supported tubulated bilayer system for evaluating protein-mediated membrane remodeling.Chemistry and physics of lipids · 2018Article
- Critical Influence of Cosolutes and Surfaces on the Assembly of Serpin-Derived Amyloid Fibrils.Biophysical journal · 2017Article
- Cartilage-like electrostatic stiffening of responsive cryogel scaffolds.Scientific reports · 2017Article
- Production of Isolated Giant Unilamellar Vesicles under High Salt Concentrations.Frontiers in physiology · 2017Article
- α-Tocopherol Is Well Designed to Protect Polyunsaturated Phospholipids: MD Simulations.Biophysical journal · 2015Article
- Permeability of the Blood-Brain Barrier: Molecular Mechanism of Transport of Drugs and Physiologically Important Compounds.The Journal of membrane biology · 2015Review
- Phase coexistence in single-lipid membranes induced by buffering agents.Langmuir : the ACS journal of surfaces and colloids · 2014Article
- Effects of lipid interactions on model vesicle engulfment by alveolar macrophages.Biophysical journal · 2014Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to thermal motion and molecular polarizability, electrical interactions in biological systems have a dynamic character. Zwitterions are dipolar molecules that typically are highly polarizable and exhibit both a positive and a negative charge depending on the pH of the solution. We use multilamellar structures of common lipids to identify and quantify the effects of zwitterionic buffers that go beyond the control of pH. We use the fact that the repeat spacing of multilamellar lipid bilayers is a sensitive and accurate indicator of the force balance between membranes. We show that common buffers can in fact charge up neutral membranes. However, this electrostatic effect is not immediately recognized because of the concomitant modification of dispersion (van der Waals) forces. We show that although surface charging can be weak, electrostatic forces are significant even at large distances because of reduced ionic screening and reduced van der Waals attraction. The zwitterionic interactions that we identify are expected to be relevant for interfacial biological processes involving lipid bilayers, and for a wide range of biomaterials, including amino acids, detergents, and pharmaceutical drugs. An appreciation of zwitterionic electrodynamic character can lead to a better understanding of molecular interactions in biological systems and in soft materials in general.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.