ArticleCytoskeleton (Hoboken, N.J.)2011
The daughter four-membered microtubule rootlet determines anterior-posterior positioning of the eyespot in Chlamydomonas reinhardtii.
Article in Cytoskeleton (Hoboken, N.J.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Review
- Algal Ocelloids and Plant Ocelli.Plants (Basel, Switzerland) · 2022Article
- Pattern Formation and Complexity in Single Cells.Current biology : CB · 2020Review
- How Cells Measure Length on Subcellular Scales.Trends in cell biology · 2015Review
- MLT1 links cytoskeletal asymmetry to organelle placement in chlamydomonas.Cytoskeleton (Hoboken, N.J.) · 2015Article
- Independent localization of plasma membrane and chloroplast components during eyespot assembly.Eukaryotic cell · 2013Article
- Statistical method for comparing the level of intracellular organization between cells.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Centriole asymmetry determines algal cell geometry.Current opinion in plant biology · 2012Review
- Phototropin influence on eyespot development and regulation of phototactic behavior in Chlamydomonas reinhardtii.The Plant cell · 2012Article
- Miniature- and Multiple-Eyespot Loci in Chlamydomonas reinhardtii Define New Modulators of Eyespot Photoreception and Assembly.G3 (Bethesda, Md.) · 2011Article
- New insights into eyespot placement and assembly in Chlamydomonas.Bioarchitecture · 2011Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The characteristic geometry of the unicellular chlorophyte Chlamydomonas reinhardtii has contributed to its adoption as a model system for cellular asymmetry and organelle positioning. The eyespot, a photosensitive organelle, is localized asymmetrically in the cell at a precisely defined position relative to the flagella and cytoskeletal microtubule rootlets. We have isolated a mutant, named pey1 for posterior eyespot, with variable microtubule rootlet lengths. The length of the acetylated daughter four-membered (D4) microtubule rootlet correlates with the position of the eyespot, which appears in a posterior position in the majority of cells. The correlation of rootlet length with eyespot positioning was also observed in the cmu1 mutant, which has longer acetylated microtubules, and the mlt1 mutant, in which the rootlet microtubules are shorter. Observation of eyespot positioning after depolymerization of rootlet microtubules indicated that eyespot position is fixed early in eyespot development and becomes independent of the rootlet. Our data demonstrate that the length of the D4 rootlet is the major determinant of eyespot positioning on the anterior-posterior axis and are suggestive that the gene product of the PEY1 locus is a novel regulator of acetylated microtubule length.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.