ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2012
Palliative sedation at the end of life at a tertiary cancer center.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Palliative pharmacological sedation for terminally ill adults.The Cochrane database of systematic reviews · 2015Pooled it
- Article
- Article
- Refractory symptoms and end of life midazolam use in cancer patients, a single center experience.Palliative & supportive care · 2025Article
- Palliative sedation at the end of life: prevalence, characteristics and possible determinants.BMC palliative care · 2024Article
- Palliative sedation for children at end of life: a retrospective cohort study.BMC palliative care · 2022Article
- Impact of legalization of Medical Assistance in Dying on the Use of Palliative Sedation in a Tertiary Care Hospital: A Retrospective Chart Review.The American journal of hospice & palliative care · 2022Article
- Midazolam sedation in palliative medicine: retrospective study in a French center for cancer control.BMC palliative care · 2020Article
- Article
- Breaking Barriers: Prospective Study of a Cohort of Advanced Chronic Obstructive Pulmonary Disease Patients To Describe Their Survival and End-of-Life Palliative Care Requirements.Journal of palliative medicine · 2019Observational
- Palliative Sedation for the Terminally Ill Patient.CNS drugs · 2018Review
- Palliative sedation in advanced cancer patients hospitalized in a specialized palliative care unit.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
- Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: cohort study.BMJ (Clinical research ed.) · 2018Article
- Continuous palliative sedation for patients with advanced cancer at a tertiary care cancer center.BMC palliative care · 2018Article
- Review
- In-service documentation tools and statements on palliative sedation in Germany--do they meet the EAPC framework recommendations? A qualitative document analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Article
- The EAPC framework on palliative sedation and clinical practice--a questionnaire-based survey in Germany.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014Article
- Towards a standardised approach for evaluating guidelines and guidance documents on palliative sedation: study protocol.BMC palliative care · 2014Article
- Research priorities in geriatric palliative care: nonpain symptoms.Journal of palliative medicine · 2013Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to describe the use of palliative sedation (PS) its indications and outcomes in patients followed up till death by an inpatient palliative care consult team (PCCT) at a tertiary cancer center.
methodsAll patients referred for 5 years to the PCCT and followed up till death were eligible for the study. Both PCCT recordings and hospital charts were reviewed and a codified assessment was performed.
resultsOver a total of 2,033 consecutive consults, 129 patients died during admission and were eligible. Eighty-three had the indication to PS, 4% of all consults (95% confidence interval [95%CI], 3% to 5%) and 64% of eligible patients (95%CI, 56% to 73%). PS was more frequently indicated in males and in patients with recurrent dyspnea and recurrent agitation, while it was less frequently indicated in older people and in patients with cerebral metastases and recurrent drowsiness. The most frequent indications to PS were dyspnea (37%) and delirium (31%) alone or combined with other symptoms. PS was successfully achieved in 69 patients; the drugs most frequently used for PS were midazolam (46%), haloperidol (35%), and chlorpromazine (32%) and opioid dose escalation was higher in sedated patients (P < 0.01).
conclusionsPS is an important intervention in the management of terminal disease by a consulting palliative care team. Improved collaboration and communication between the hospital staff and the PCCT should be offered to meet patients' needs when PS is required.
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