Evidence map›Paper›PMID 21764803›Full record

ReviewActa biochimica et biophysica Sinica2011

Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases.

Wenyan Xu, Liling Li, Liangcheng Du, Ninghua Tan

Open access · greenAbstract readReview
In one paragraph

Review in Acta biochimica et biophysica Sinica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. The Catalytic Mechanism of the Marine-Derived Macrocyclase PatGmac.Chemistry (Weinheim an der Bergstrasse, Germany) · 2016
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Wenyan XuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, China.
Liling Li
Liangcheng Du
Ninghua Tan
Kunming Institute of Botany · CNChinese Academy of Sciences · CNUniversity of Nebraska–Lincoln · US

Funding

EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015468 · NCRR · UNIVERSITY OF NEBRASKA LINCOLN · PI PAUL, PREM S · 2000 to 2000
$2.0M
NCRR NIH HHS RR015468-01
6 · The paper itself

Abstract

An increasing number of cyclopeptides have been discovered as products of ribosomal synthetic pathway. The biosynthetic study of these cyclopeptides has revealed interesting new mechanisms for cyclization. This review highlighted the recent discoveries in cyclization mechanisms for cyclopeptides synthesized independently of non-ribosomal peptide synthetases, including endopeptidase-catalyzed cyclization, intein-mediated cyclization, and peptide synthetase-catalyzed cyclization. This information may help to design hybrid ribosomal and non-ribosomal biosynthetic systems to produce novel cyclopeptides with various bioactivities.

Indexed as

Peptide BiosynthesisCyclizationPeptides, CyclicPeptide SynthasesRibosomal ProteinsRibosomesnon-ribosomal peptide synthasePeptides, CyclicPeptide SynthasesRibosomal Proteins

Identifiers

PMID21764803
PMCPMC3180235
OpenAlexW2140239032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.