Evidence map›Paper›PMID 21763486›Full record

ArticleAmerican journal of human genetics2011

Population structure can inflate SNP-based heritability estimates.

Sharon R Browning, Brian L Browning

Abstract readLetterComment
In one paragraph

Article in American journal of human genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Interpreting SNP heritability in admixed populations.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Using neuroimaging genomics to investigate the evolution of human brain structure.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Polygenic Architecture of Human Neuroanatomical Diversity.Cerebral cortex (New York, N.Y. : 1991) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sharon R Browning
Brian L Browning

Funding

Improved gene mapping for whole genome dataR01HG005701 · NHGRI · UNIVERSITY OF WASHINGTON · PI BROWNING, BRIAN LEE · 2010 to 2024
$4.4M
Improving genotype call accuracyR01HG004960 · NHGRI · UNIVERSITY OF WASHINGTON · PI BROWNING, BRIAN LEE · 2009 to 2014
$1.4M
NHGRI NIH HHS R01 HG004960NHGRI NIH HHS R01HG004960NHGRI NIH HHS R01 HG005701NHGRI NIH HHS R01HG005701Wellcome Trust 076113
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetics, PopulationPolymorphism, Single NucleotideQuantitative Trait, HeritableBipolar DisorderComputer SimulationCrohn DiseaseDiabetes Mellitus, Type 1GenotypeGeographyHumansModels, GeneticPhenotypeSoftwareUnited KingdomWhite People

Identifiers

PMID21763486
PMCPMC3135810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.