Evidence map›Paper›PMID 21762820›Full record

ArticleAdvances in virus research2011

Mycoviruses, RNA silencing, and viral RNA recombination.

Donald L Nuss

Abstract read
In one paragraph

Article in Advances in virus research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
36.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Expanding Mycovirome ofJournal of fungi (Basel, Switzerland) · 2024
    Review
  8. Replication of single viruses across the kingdoms, Fungi, Plantae, and Animalia.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Argonaute-independent, Dicer-dependent antiviral defense against RNA viruses.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Disruption of theRNA (New York, N.Y.) · 2023
    Article
  11. Review
  12. ICTV Virus Taxonomy Profile:The Journal of general virology · 2023
    Article
  13. Article
  14. Article
  15. Interference of Small RNAs inJournal of fungi (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Donald L NussInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland, USA.
Institute for Bioscience and Biotechnology Research

Funding

HYPOVIRUS MOLECULAR BIOLOGYR01GM055981 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI NUSS, DONALD L · 1997 to 2012
$4.2M
NIGMS NIH HHS R01 GM055981
6 · The paper itself

Abstract

In contrast to viruses of plants and animals, viruses of fungi, mycoviruses, uniformly lack an extracellular phase to their replication cycle. The persistent, intracellular nature of the mycovirus life cycle presents technical challenges to experimental design. However, these properties, coupled with the relative simplicity and evolutionary position of the fungal host, also provide opportunities for examining fundamental aspects of virus-host interactions from a perspective that is quite different from that pertaining for most plant and animal virus infections. This chapter presents support for this view by describing recent advances in the understanding of antiviral defense responses against one group of mycoviruses for which many of the technical experimental challenges have been overcome, the hypoviruses responsible for hypovirulence of the chestnut blight fungus Cryphonectria parasitica. The findings reveal new insights into the induction and suppression of RNA silencing as an antiviral defense response and an unexpected role for RNA silencing in viral RNA recombination.

Indexed as

RNA InterferenceAscomycotaDrug Resistance, ViralGene Expression RegulationPlant DiseasesPlantsRNARNA, ViralRNA VirusesSignal TransductionVirus ReplicationRNARNA, recombinantRNA, Viral

Identifiers

PMID21762820
PMCPMC3313461
OpenAlexW149976783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.