ArticleNanoscale research letters2011
Comparison of immature and mature bone marrow-derived dendritic cells by atomic force microscopy.
Article in Nanoscale research letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
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- Endotoxin-Tolerance Mimicking to Study TLR in Promotion of Tolerogenic DCs and Tr1 Cells.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Insights into dendritic cell maturation during infection with application of advanced imaging techniques.Frontiers in cellular and infection microbiology · 2023Review
- Distinct speed and direction memories of migrating dendritic cells diversify their search strategies.Biophysical journal · 2022Article
- Respiratory Nasal Mucosa in Chronic Rhinosinusitis with Nasal Polyps versus COVID-19: Histopathology, Electron Microscopy Analysis and Assessing of Tissue Interleukin-33.Journal of clinical medicine · 2021Article
- In Vivo Implications of Potential Probiotic Lactobacillus reuteri LR6 on the Gut and Immunological Parameters as an Adjuvant Against Protein Energy Malnutrition.Probiotics and antimicrobial proteins · 2020Article
- Biophysical and biomechanical properties of neural progenitor cells as indicators of developmental neurotoxicity.Archives of toxicology · 2019Article
- Properties of immature and mature dendritic cells: phenotype, morphology, phagocytosis, and migration.RSC advances · 2019Article
- Automated generation of immature dendritic cells in a single-use system.Journal of immunological methods · 2018Article
- Optimization ofBone marrow research · 2018Article
- Applying Pattern Recognition to High-Resolution Images to Determine Cellular Signaling Status.IEEE transactions on nanobioscience · 2017Article
- Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination.Small (Weinheim an der Bergstrasse, Germany) · 2016Article
- Phenotypic and functional comparison of two distinct subsets of programmable cell of monocytic origin (PCMOs)-derived dendritic cells with conventional monocyte-derived dendritic cells.Cellular & molecular immunology · 2016Article
- Can dendritic cells improve whole cancer cell vaccines based on immunogenically killed cancer cells?Oncoimmunology · 2015Article
- The mechanisms of up-regulation of dendritic cell activity by oxidative stress.Journal of leukocyte biology · 2014Article
- The influence of aminophylline on the nanostructure and nanomechanics of T lymphocytes: an AFM study.Nanoscale research letters · 2014Article
- FC-98 regulates TLR9-mediated of CXCL-10 expression in dendritic cells via MAPK and STAT1 signaling pathway.BioMed research international · 2014Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A comparative study of immature and mature bone marrow-derived dendritic cells (BMDCs) was first performed through an atomic force microscope (AFM) to clarify differences of their nanostructure and adhesion force. AFM images revealed that the immature BMDCs treated by granulocyte macrophage-colony stimulating factor plus IL-4 mainly appeared round with smooth surface, whereas the mature BMDCs induced by lipopolysaccharide displayed an irregular shape with numerous pseudopodia or lamellapodia and ruffles on the cell membrane besides becoming larger, flatter, and longer. AFM quantitative analysis further showed that the surface roughness of the mature BMDCs greatly increased and that the adhesion force of them was fourfold more than that of the immature BMDCs. The nano-features of the mature BMDCs were supported by a high level of IL-12 produced from the mature BMDCs and high expression of MHC-II on the surface of them. These findings provide a new insight into the nanostructure of the immature and mature BMDCs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.