Evidence map›Paper›PMID 21762363›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2011

An innovative piezoelectric-based method for measuring pulse wave velocity in patients with hypertension.

John C Murphy, Katherine Morrison, James McLaughlin, Ganesh Manoharan, Aa Jennifer Adgey

Abstract readComparative Study
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John C MurphyThe Heart Centre, Royal Victoria Hospital, Belfast, Northern Ireland.
Katherine Morrison
James McLaughlin
Ganesh Manoharan
Aa Jennifer Adgey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulse wave velocity (PWV) is an accepted surrogate marker of arterial stiffness and may be a useful tool for assessing cardiovascular risk in hypertensive patients. The authors sought to compare a novel polyvinylidene fluoride (PVDF) piezoelectric-based sensing device for measuring PWV in the arm with a validated SphygmoCor device (AtCor Medical, West Ryde, Australia) in normal and hypertensive patients. They also sought to compare measured PWV in the forearm (brachial-radial PWV [BRPWV]) with values obtained in the carotid-radial segment (carotid-radial PWV [CRPWV]). Under standardized conditions, CRPWV in 108 normotensive patients with both devices was measured. BRPWV was measured with the PVDF device. Identical measurements were made in a group of 82 hypertensive patients before and after optimization of blood pressure control. Mean CRPWV was 8.7 m/s in the normotensive group and 9.4 m/s in the hypertensive group. Mean BRPWV was 9.2 m/s in the normotensive group and 10.3 m/s in the hypertensive group. There was excellent correlation between the 2 devices when comparing individual CRPWV values (normotensive group, R(2) = 0.92; mean bias 0.04 m/s; hypertensive group, R(2) = 0.89, mean bias 0.08 m/s). Correlation was also favorable when measuring changes in CRPWV in hypertensive patients undergoing pharmacotherapy (PVDF -0.52 ± 0.90 m/s vs SphygmoCor -0.53 ± 1.01 m/s; R(2) = 0.81). Measured values for BRPWV were significantly higher than CRPWV values, and this discrepancy was more marked in the hypertensive group. The PVDF piezoelectric device has excellent correlation with the validated SphygmoCor device when measuring PWV. This novel device may have an important role in patients with conditions such as hypertension.

Indexed as

Blood Flow VelocityPulsatile FlowVascular ResistanceAdultAgedCarotid ArteriesDiagnostic Techniques, CardiovascularEquipment DesignFemaleHumansHypertensionMaleMiddle AgedMuscle, Smooth, VascularPatient SelectionReproducibility of Results

Identifiers

PMID21762363
PMCPMC8108833

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.