Evidence map›Paper›PMID 21762127›Full record

ReviewClinical and experimental immunology2011

Bringing immunoglobulin knowledge up to date: how should we treat today?

S Misbah, T Kuijpers, J van der Heijden, B Grimbacher, D Guzman, J Orange

Open access · greenAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Immunoglobulin therapy for refractory Crohn's disease.Therapeutic advances in gastroenterology · 2014
    Article
  4. Review
  5. Review
  6. Broadening the translational immunology landscape.Clinical and experimental immunology · 2012
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

S MisbahJohn Radcliffe Hospital, Oxford, UK Emma Children's Hospital, Amsterdam, the Netherlands Royal Free Hospital and University College London, London, UK. siraj.misbah@orh.nhs.uk
T Kuijpers
J van der Heijden
B Grimbacher
D Guzman
J Orange
Emma Kinderziekenhuis · NLUniversity College London · GBJohn Radcliffe Hospital · GBUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin (Ig) therapy is constantly evolving. Advances in the basic and clinical science of immunoglobulins have provided new perspectives in using polyclonal IgG to treat patients with primary immunodeficiencies. Recent meta-analyses of patient data and outcomes, optimization of IgG administration and better understanding of the IgG receptor variability and clinical effect are new concepts which practising immunologists can use in tailoring their approach to treating patients with primary immunodeficiencies. This manuscript presents the proceedings of a satellite symposium, held in conjunction with the European Society for Immunodeficiencies (ESID) 2010 meeting, to inform attendees about new scientific concepts in IgG therapy, with the goal of empowering expert level evaluation of what optimal IgG therapy is today.

Indexed as

Immunoglobulin GCongresses as TopicC-Reactive ProteinHumansImmunization, PassiveImmunologic Deficiency SyndromesInjections, IntravenousInjections, SubcutaneousMeta-Analysis as TopicReceptors, IgGC-Reactive ProteinImmunoglobulin GReceptors, IgG

Identifiers

PMID21762127
PMCPMC3193915
OpenAlexW1910584584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.