Evidence map›Paper›PMID 21761267›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2011

Nuclear myocardial perfusion imaging with a novel cadmium-zinc-telluride detector SPECT/CT device: first validation versus invasive coronary angiography.

Michael Fiechter, Jelena R Ghadri, Silke M Kuest, Aju P Pazhenkottil, Mathias Wolfrum, Rene N Nkoulou, Robert Goetti, Oliver Gaemperli, Philipp A Kaufmann

Open access · bronzeAbstract readValidation Study
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Multi-center study of inter-rater reproducibility, image quality, and diagnostic accuracy of CZT versus conventional SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  6. Reduced acquisition time for thallium myocardial perfusion imaging with large field cadmium-zinc-telluride SPECT/CT cameras: An equivalence study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Dedicated cardiac CZT SPECT is steadily moving to achieve its destiny.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  12. Clinical performance of Rb-82 myocardial perfusion PET and Tc-99m-based SPECT in patients with extreme obesity.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  13. Impact of data-driven cardiac respiratory motion correction on the extent and severity of myocardial perfusion defects with free-breathing CZT SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  14. Prognostic value of one millisievert exercise myocardial perfusion imaging in patients without known coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  15. Feasibility of data-driven cardiac respiratory motion correction of myocardial perfusion CZT SPECT: A pilot study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  16. Automatic Valve Plane Localization in Myocardial Perfusion SPECT/CT by Machine Learning: Anatomic and Clinical Validation.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2017
    Article
  17. Review
  18. NovelNuclear medicine and biology · 2016
    Article
  19. Newer generation cameras are preferred.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Michael FiechterDepartment of Radiology, Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Jelena R Ghadri
Silke M Kuest
Aju P Pazhenkottil
Mathias Wolfrum
Rene N Nkoulou
Robert Goetti
Oliver Gaemperli
Philipp A Kaufmann
University Hospital of Zurich · CHSwiss Integrative Center for Human Health · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe evaluated the diagnostic accuracy of attenuation corrected nuclear myocardial perfusion imaging (MPI) with a novel hybrid single photon emission computed tomography (SPECT)/CT device consisting of an ultrafast dedicated cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors integrated onto a multislice CT scanner to detect coronary artery disease (CAD). Invasive coronary angiography served as the standard of reference.

methodsThe study population included 66 patients (79% men; mean age 63 ± 11 years) who underwent 1-day (99m)Tc-tetrofosmin pharmacological stress/rest examination and angiography within 3 months. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) as well as accuracy of the CT X-ray based attenuation corrected CZT MPI for detection of CAD (≥ 50% luminal narrowing) was calculated on a per-patient basis.

resultsThe prevalence of angiographic CAD in the study population was 82%. Sensitivity, specificity, PPV, NPV and accuracy were 87, 67, 92, 53 and 83%, respectively.

conclusionIn this first report on CZT SPECT/CT MPI comparison versus angiography we confirm a high accuracy for detection of angiographically documented CAD.

Indexed as

CadmiumCoronary AngiographyPositron-Emission TomographyTelluriumTomography, X-Ray ComputedZincAdultAgedAged, 80 and overCoronary Artery DiseaseFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedMultimodal ImagingCadmiumCdZnTeTelluriumZinc

Identifiers

PMID21761267
OpenAlexW2061040105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.