ReviewAnnals of biomedical engineering2011
Endothelial cell micropatterning: methods, effects, and applications.
Review in Annals of biomedical engineering, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Micropatterning transcriptionally and phenotypically reprograms endothelial cells.Acta biomaterialia · 2026Article
- Development of a Stereolithography 3D Printing-Based Micropatterning Method to Study Endothelial-to-Mesenchymal Transition Mechanobiology.Annals of biomedical engineering · 2026Article
- Biomechanical research using advanced micro-nano devices: In-Vitro cell Characterization focus.Journal of advanced research · 2025Review
- A biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration.Bioactive materials · 2024Article
- Cell chirality exhibition of brain microvascular endothelial cells is dependent on micropattern width.RSC advances · 2022Article
- Brain microvasculature endothelial cell orientation on micropatterned hydrogels is affected by glucose level variations.Scientific reports · 2021Article
- Micropatterning Transmission Electron Microscopy Grids to Direct Cell Positioning within Whole-Cell Cryo-Electron Tomography Workflows.Journal of visualized experiments : JoVE · 2021Article
- The vascular niche in next generation microphysiological systems.Lab on a chip · 2021Review
- Single cell morphological metrics and cytoskeletal alignment regulate VCAM-1 protein expression.Biochemical and biophysical research communications · 2021Article
- The Effects of Topographic Micropatterning on Endothelial Colony-Forming Cells.Tissue engineering. Part A · 2021Article
- A simplified approach to control cell adherence on biologically derived in vitro cell culture scaffolds by direct UV-mediated RGD linkage.Journal of materials science. Materials in medicine · 2020Article
- Article
- Quantifying the effects of engineered nanomaterials on endothelial cell architecture and vascular barrier integrity using a cell pair model.Nanoscale · 2019Article
- Focal adhesion clustering drives endothelial cell morphology on patterned surfaces.Journal of the Royal Society, Interface · 2019Article
- State-of-the-Art Strategies for the Vascularization of Three-Dimensional Engineered Organs.Vascular specialist international · 2019Review
- Surface patterning of a novel PEG-functionalized poly-l-lactide polymer to improve its biocompatibility: Applications to bioresorbable vascular stents.Journal of biomedical materials research. Part B, Applied biomaterials · 2019Article
- Mechanical response of an epithelial island subject to uniaxial stretch on a hybrid silicone substrate.Cellular and molecular bioengineering · 2019Article
- Static spatial growth restriction micropatterning of endothelial colony forming cells influences their morphology and gene expression.PloS one · 2019Article
- An important step towards a prevascularized islet microencapsulation device: in vivo prevascularization by combination of mesenchymal stem cells on micropatterned membranes.Journal of materials science. Materials in medicine · 2018Article
- Micropatterned immobilization of membrane-mimicking polymer and peptides for regulation of cell behaviorsRSC advances · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The effects of flow on endothelial cells (ECs) have been widely examined for the ability of fluid shear stress to alter cell morphology and function; however, the effects of EC morphology without flow have only recently been observed. An increase in lithographic techniques in cell culture spurred a corresponding increase in research aiming to confine cell morphology. These studies lead to a better understanding of how morphology and cytoskeletal configuration affect the structure and function of the cells. This review examines EC micropatterning research by exploring both the many alternative methods used to alter EC morphology and the resulting changes in cellular shape and phenotype. Micropatterning induced changes in EC proliferation, apoptosis, cytoskeletal organization, mechanical properties, and cell functionality. Finally, the ways these cellular manipulation techniques have been applied to biomedical engineering research, including angiogenesis, cell migration, and tissue engineering, are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.