ArticleDigestive diseases and sciences2011
Endoscopic resection of ampullary adenomas: complications and outcomes.
Article in Digestive diseases and sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Therapeutic strategies and outcomes in the management of ampullary tumours: meta-analysis.BJS open · 2026Pooled it
- Prophylactic pancreatic duct stenting to reduce the risk of post-ampullectomy pancreatitis: a comprehensive review and meta-analysis of 1858 patients.Surgical endoscopy · 2024Pooled it
- Long-term recurrence after endoscopic versus surgical ampullectomy of sporadic ampullary adenomas: a systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- A Comparison of Clinical Outcomes between Endoscopic Resection and Surgical Resection in Ampullary Tumors.Medicina (Kaunas, Lithuania) · 2020Pooled it
- Endoscopic papillectomy for neoplastic ampullary lesions: A systematic review with pooled analysis.United European gastroenterology journal · 2020Pooled it
- The Significance of Histopathological Findings on Clinical Outcomes in Endoscopic Papillectomy with Endocut.Journal of clinical medicine · 2023Article
- Anticoagulation and antiplatelet management in gastrointestinal endoscopy: A review of current evidence.World journal of gastrointestinal endoscopy · 2020Review
- Systematic Review with Meta-Analysis: Endoscopic and Surgical Resection for Ampullary Lesions.Journal of clinical medicine · 2020Review
- An Unusual Cause of Acute Pancreatitis: Intraductal Tubulovillous Ampullary Adenoma.Journal of the Canadian Association of Gastroenterology · 2020Article
- Article
- Endoscopic Resection of Ampullary Tumours: Long-term Outcomes and Adverse Events.Journal of the Canadian Association of Gastroenterology · 2020Article
- Study Protocol of the ESAP Study: Endoscopic Papillectomy vs. Surgical Ampullectomy vs. Pancreaticoduodenectomy for Ampullary Neoplasm-A Pancreas2000/EPC Study.Frontiers in medicine · 2020Article
- Diagnosis, risk stratification, and management of ampullary dysplasia by DNA flow cytometric analysis of paraffin-embedded tissue.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019Article
- The efficacy of prophylactic pancreatic stents against complications of post-endoscopic papillectomy or endoscopic ampullectomy: a systematic review and meta-analysis.Therapeutic advances in gastroenterology · 2019Article
- Endoscopic papillectomy of benign ampullary lesions: Outcomes from a multicenter study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2018Article
- Endoscopic management of adenomatous ampullary lesions.World journal of methodology · 2015Review
- Recurrences are common after endoscopic ampullectomy for adenoma in the familial adenomatous polyposis (FAP) syndrome.Surgical endoscopy · 2014Article
- Prophylactic pancreatic stent placement for endoscopic duodenal ampullectomy: a single-center retrospective study.Gut and liver · 2014Article
- Clinicopathologic characteristics associated with complications and long-term outcomes of endoscopic papillectomy for adenoma.Yonsei medical journal · 2014Article
- Endoscopic resection of ampullary lesions: a single-center 8-year retrospective cohort study of 91 patients with long-term follow-up.Surgical endoscopy · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimAmpullary adenomas have the potential to progress from benign to malignant lesions. Endoscopic ampullectomy as curative therapy has gained credibility as a safe and effective alternative to surgical resection. This study was designed to assess outcomes of endoscopic resection of ampullary neoplasms at a single center.
methodsBetween May 1996 and August 2009, all patients referred to our center for endoscopic resection of an ampullary lesion were retrospectively identified. Patients were followed for complications and endoscopic surveillance performed per protocol to assess for recurrence.
resultsEndoscopic ampullectomy for adenoma was performed in 38 patients (22 females; mean age, 54.3 years, range, 22-85 years), with high-grade dysplasia (HGD) diagnosed in 6 and low-grade dysplasia (LGD) in 32. A direct relationship was observed between HGD and tumor size (P = 0.03). Lesions less than 2.5 cm in size demonstrated no evidence of invasion. Mean follow-up duration was 17.2 ± 2 months (range, 0-82.5 months). Complications were uniformly mild and occurred in 6 (16%) patients: bleeding in 2, pancreatitis in 3, and infection in 1. Adenoma recurrence was documented in 6 (16%) patients, 4 with LGD and 2 with HGD; no patients had tumors that progressed from LGD to HGD or HGD to cancer. Kaplan-Meier analysis showed insignificant differences in recurrence between HGD and LGD groups (P = 0.13).
conclusionsEndoscopic ampullectomy is a safe and effective treatment for benign ampullary neoplasms and should become the treatment of choice rather than surgical therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.